Gene-specific Copy Number Variation Probe-CDKN1A
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| Catalog: |
CNVFP-CDKN1A-02517 |
| Classification: |
Copy Number Variation |
| Description: |
Our Gene-specific Copy Number Variation Probes usually target the flanks of the target gene (CDKN1A). The product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We provide CNV FISH Probes with a variety of dye color combinations to meet various challenges. Probe products not only provide some classic color combinations but also provide customized probe services. |
| Application: |
CDKN1A Gene-specific copy number variation probes are mainly used to detect the copy number variation related to CDKN1A genes. This product achieves the purpose of detection by hybridizing with the CDKN1A gene. Due to this design method, our probe products can detect the amplification and deletion of target genes on chromosomes through FISH. |
| Category: |
Copy Number Variation |
| Probe Kits Volume (µL): |
40 μL |
| Quantity: |
20 Tests |
| Hybridization Solution (µL): |
200 μL |
| Turnaround Time: |
7-10 Business Days |
| Shipping Time: |
1-2 Day Expedited Shipping |
| Storage Conditions: |
Store at -20℃ and avoid light; |
| Shipping Conditions: |
-20℃ |
Gene Details
| Gene Name |
Cyclin Dependent Kinase Inhibitor 1A |
| Gene Summary [Provided by RefSeq] |
This gene encodes a potent cyclin-dependent kinase inhibitor. The encoded protein binds to and inhibits the activity of cyclin-cyclin-dependent kinase2 or -cyclin-dependent kinase4 complexes, and thus functions as a regulator of cell cycle progression at G1. The expression of this gene is tightly controlled by the tumor suppressor protein p53, through which this protein mediates the p53-dependent cell cycle G1 phase arrest in response to a variety of stress stimuli. This protein can interact with proliferating cell nuclear antigen, a DNA polymerase accessory factor, and plays a regulatory role in S phase DNA replication and DNA damage repair. This protein was reported to be specifically cleaved by CASP3-like caspases, which thus leads to a dramatic activation of cyclin-dependent kinase2, and may be instrumental in the execution of apoptosis following caspase activation. Mice that lack this gene have the ability to regenerate damaged or missing tissue. Multiple alternatively spliced variants have been found for this gene. [provided by RefSeq, Sep 2015] |
| Gene Symbol |
CDKN1A |
| Location |
6p21.2 |
| Chromosome |
Chromosome6 |
| Coordinates |
This gene maps to 36644236-36655116 in GRCh37 coordinates. |
| Species |
Human |
Dye Colors:
OR
RE
GO
GR
AQ
Order Sheet
| Number |
Dye Color |
Order Name |
Absorbance Maximum |
Emission Maximum |
Add to Cart |
| 1 |
OR
|
CNVFP-CDKN1A-02517-OR |
573nm |
548nm |
|
| 2 |
RE
|
CNVFP-CDKN1A-02517-RE |
599nm |
580nm |
|
| 3 |
GO
|
CNVFP-CDKN1A-02517-GO |
551nm |
525nm |
|
| 4 |
GR
|
CNVFP-CDKN1A-02517-GR |
515nm |
491nm |
|
| 5 |
AQ
|
CNVFP-CDKN1A-02517-AQ |
467nm |
418nm |
|
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