Gene-specific Copy Number Variation Probe-CD59
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Catalog: |
CNVFP-CD59-02310 |
Classification: |
Copy Number Variation |
Description: |
Our Gene-specific Copy Number Variation Probes usually target the flanks of the target gene (CD59). The product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We provide CNV FISH Probes with a variety of dye color combinations to meet various challenges. Probe products not only provide some classic color combinations but also provide customized probe services. |
Application: |
CD59 Gene-specific copy number variation probes are mainly used to detect the copy number variation related to CD59 genes. This product achieves the purpose of detection by hybridizing with the CD59 gene. Due to this design method, our probe products can detect the amplification and deletion of target genes on chromosomes through FISH. |
Category: |
Copy Number Variation |
Probe Kits Volume (µL): |
40 μL |
Quantity: |
20 Tests |
Hybridization Solution (µL): |
200 μL |
Turnaround Time: |
7-10 Business Days |
Shipping Time: |
1-2 Day Expedited Shipping |
Storage Conditions: |
Store at -20℃ and avoid light; |
Shipping Conditions: |
-20℃ |
Gene Details
Gene Name |
CD59 Molecule (CD59 Blood Group) |
Gene Summary [Provided by RefSeq] |
This gene encodes a cell surface glycoprotein that regulates complement-mediated cell lysis, and it is involved in lymphocyte signal transduction. This protein is a potent inhibitor of the complement membrane attack complex, whereby it binds complement C8 and/or C9 during the assembly of this complex, thereby inhibiting the incorporation of multiple copies of C9 into the complex, which is necessary for osmolytic pore formation. This protein also plays a role in signal transduction pathways in the activation of T cells. Mutations in this gene cause CD59 deficiency, a disease resulting in hemolytic anemia and thrombosis, and which causes cerebral infarction. Multiple alternatively spliced transcript variants, which encode the same protein, have been identified for this gene. [provided by RefSeq, Jul 2008] |
Gene Symbol |
CD59 |
Location |
11p13 |
Chromosome |
Chromosome11 |
Coordinates |
This gene maps to 33724555-33758025 in GRCh37 coordinates. |
Species |
Human |
Dye Colors:
OR
RE
GO
GR
AQ
Order Sheet
Number |
Dye Color |
Order Name |
Absorbance Maximum |
Emission Maximum |
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1 |
OR
|
CNVFP-CD59-02310-OR |
573nm |
548nm |
|
2 |
RE
|
CNVFP-CD59-02310-RE |
599nm |
580nm |
|
3 |
GO
|
CNVFP-CD59-02310-GO |
551nm |
525nm |
|
4 |
GR
|
CNVFP-CD59-02310-GR |
515nm |
491nm |
|
5 |
AQ
|
CNVFP-CD59-02310-AQ |
467nm |
418nm |
|
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