Gene-specific Copy Number Variation Probe-CD40
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| Catalog: |
CNVFP-CD40-02318 |
| Classification: |
Copy Number Variation |
| Description: |
Our Gene-specific Copy Number Variation Probes usually target the flanks of the target gene (CD40). The product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We provide CNV FISH Probes with a variety of dye color combinations to meet various challenges. Probe products not only provide some classic color combinations but also provide customized probe services. |
| Application: |
CD40 Gene-specific copy number variation probes are mainly used to detect the copy number variation related to CD40 genes. This product achieves the purpose of detection by hybridizing with the CD40 gene. Due to this design method, our probe products can detect the amplification and deletion of target genes on chromosomes through FISH. |
| Category: |
Copy Number Variation |
| Probe Kits Volume (µL): |
40 μL |
| Quantity: |
20 Tests |
| Hybridization Solution (µL): |
200 μL |
| Turnaround Time: |
7-10 Business Days |
| Shipping Time: |
1-2 Day Expedited Shipping |
| Storage Conditions: |
Store at -20℃ and avoid light; |
| Shipping Conditions: |
-20℃ |
Gene Details
| Gene Name |
CD40 Molecule |
| Gene Summary [Provided by RefSeq] |
This gene is a member of the TNF-receptor superfamily. The encoded protein is a receptor on antigen-presenting cells of the immune system and is essential for mediating a broad variety of immune and inflammatory responses including T cell-dependent immunoglobulin class switching, memory B cell development, and germinal center formation. AT-hook transcription factor AKNA is reported to coordinately regulate the expression of this receptor and its ligand, which may be important for homotypic cell interactions. Adaptor protein TNFR2 interacts with this receptor and serves as a mediator of the signal transduction. The interaction of this receptor and its ligand is found to be necessary for amyloid-beta-induced microglial activation, and thus is thought to be an early event in Alzheimer disease pathogenesis. Mutations affecting this gene are the cause of autosomal recessive hyper-IgM immunodeficiency type 3 (HIGM3). Multiple alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported. [provided by RefSeq, Nov 2014] |
| Gene Symbol |
CD40 |
| Location |
20q13.12 |
| Chromosome |
Chromosome20 |
| Coordinates |
This gene maps to 44746905-44758384 in GRCh37 coordinates. |
| Species |
Human |
Dye Colors:
OR
RE
GO
GR
AQ
Order Sheet
| Number |
Dye Color |
Order Name |
Absorbance Maximum |
Emission Maximum |
Add to Cart |
| 1 |
OR
|
CNVFP-CD40-02318-OR |
573nm |
548nm |
|
| 2 |
RE
|
CNVFP-CD40-02318-RE |
599nm |
580nm |
|
| 3 |
GO
|
CNVFP-CD40-02318-GO |
551nm |
525nm |
|
| 4 |
GR
|
CNVFP-CD40-02318-GR |
515nm |
491nm |
|
| 5 |
AQ
|
CNVFP-CD40-02318-AQ |
467nm |
418nm |
|
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