Gene-specific Copy Number Variation Probe-CD274
Add to Cart
| Catalog: |
CNVFP-CD274-02343 |
| Classification: |
Copy Number Variation |
| Description: |
Our Gene-specific Copy Number Variation Probes usually target the flanks of the target gene (CD274). The product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We provide CNV FISH Probes with a variety of dye color combinations to meet various challenges. Probe products not only provide some classic color combinations but also provide customized probe services. |
| Application: |
CD274 Gene-specific copy number variation probes are mainly used to detect the copy number variation related to CD274 genes. This product achieves the purpose of detection by hybridizing with the CD274 gene. Due to this design method, our probe products can detect the amplification and deletion of target genes on chromosomes through FISH. |
| Category: |
Copy Number Variation |
| Probe Kits Volume (µL): |
40 μL |
| Quantity: |
20 Tests |
| Hybridization Solution (µL): |
200 μL |
| Turnaround Time: |
7-10 Business Days |
| Shipping Time: |
1-2 Day Expedited Shipping |
| Storage Conditions: |
Store at -20℃ and avoid light; |
| Shipping Conditions: |
-20℃ |
Gene Details
| Gene Name |
CD274 Molecule |
| Gene Summary [Provided by RefSeq] |
This gene encodes an immune inhibitory receptor ligand that is expressed by hematopoietic and non-hematopoietic cells, such as T cells and B cells and various types of tumor cells. The encoded protein is a type I transmembrane protein that has immunoglobulin V-like and C-like domains. Interaction of this ligand with its receptor inhibits T-cell activation and cytokine production. During infection or inflammation of normal tissue, this interaction is important for preventing autoimmunity by maintaining homeostasis of the immune response. In tumor microenvironments, this interaction provides an immune escape for tumor cells through cytotoxic T-cell inactivation. Expression of this gene in tumor cells is considered to be prognostic in many types of human malignancies, including colon cancer and renal cell carcinoma. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2015] |
| Gene Symbol |
CD274 |
| Location |
9p24.1 |
| Chromosome |
Chromosome9 |
| Coordinates |
This gene maps to 5450502-5470567 in GRCh37 coordinates. |
| Species |
Human |
Dye Colors:
OR
RE
GO
GR
AQ
Order Sheet
| Number |
Dye Color |
Order Name |
Absorbance Maximum |
Emission Maximum |
Add to Cart |
| 1 |
OR
|
CNVFP-CD274-02343-OR |
573nm |
548nm |
|
| 2 |
RE
|
CNVFP-CD274-02343-RE |
599nm |
580nm |
|
| 3 |
GO
|
CNVFP-CD274-02343-GO |
551nm |
525nm |
|
| 4 |
GR
|
CNVFP-CD274-02343-GR |
515nm |
491nm |
|
| 5 |
AQ
|
CNVFP-CD274-02343-AQ |
467nm |
418nm |
|
Other Products
