Gene-specific Copy Number Variation Probe-CCM2
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| Catalog: |
CNVFP-CCM2-02124 |
| Classification: |
Copy Number Variation |
| Description: |
Our Gene-specific Copy Number Variation Probes usually target the flanks of the target gene (CCM2). The product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We provide CNV FISH Probes with a variety of dye color combinations to meet various challenges. Probe products not only provide some classic color combinations but also provide customized probe services. |
| Application: |
CCM2 Gene-specific copy number variation probes are mainly used to detect the copy number variation related to CCM2 genes. This product achieves the purpose of detection by hybridizing with the CCM2 gene. Due to this design method, our probe products can detect the amplification and deletion of target genes on chromosomes through FISH. |
| Category: |
Copy Number Variation |
| Probe Kits Volume (µL): |
40 μL |
| Quantity: |
20 Tests |
| Hybridization Solution (µL): |
200 μL |
| Turnaround Time: |
7-10 Business Days |
| Shipping Time: |
1-2 Day Expedited Shipping |
| Storage Conditions: |
Store at -20℃ and avoid light; |
| Shipping Conditions: |
-20℃ |
Gene Details
| Gene Name |
CCM2 Scaffolding Protein |
| Gene Summary [Provided by RefSeq] |
This gene encodes a scaffold protein that functions in the stress-activated p38 Mitogen-activated protein kinase (MAPK) signaling cascade. The protein interacts with SMAD specific E3 ubiquitin protein ligase 1 (also known as SMURF1) via a phosphotyrosine binding domain to promote RhoA degradation. The protein is required for normal cytoskeletal structure, cell-cell interactions, and lumen formation in endothelial cells. Mutations in this gene result in cerebral cavernous malformations. Multiple transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Nov 2009] |
| Gene Symbol |
CCM2 |
| Location |
7p13 |
| Chromosome |
Chromosome7 |
| Coordinates |
This gene maps to 45039344-45116069 in GRCh37 coordinates. |
| Species |
Human |
Dye Colors:
OR
RE
GO
GR
AQ
Order Sheet
| Number |
Dye Color |
Order Name |
Absorbance Maximum |
Emission Maximum |
Add to Cart |
| 1 |
OR
|
CNVFP-CCM2-02124-OR |
573nm |
548nm |
|
| 2 |
RE
|
CNVFP-CCM2-02124-RE |
599nm |
580nm |
|
| 3 |
GO
|
CNVFP-CCM2-02124-GO |
551nm |
525nm |
|
| 4 |
GR
|
CNVFP-CCM2-02124-GR |
515nm |
491nm |
|
| 5 |
AQ
|
CNVFP-CCM2-02124-AQ |
467nm |
418nm |
|
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