Gene-specific Copy Number Variation Probe-CBL
Add to Cart
| Catalog: |
CNVFP-CBL-01891 |
| Classification: |
Copy Number Variation |
| Description: |
Our Gene-specific Copy Number Variation Probes usually target the flanks of the target gene (CBL). The product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We provide CNV FISH Probes with a variety of dye color combinations to meet various challenges. Probe products not only provide some classic color combinations but also provide customized probe services. |
| Application: |
CBL Gene-specific copy number variation probes are mainly used to detect the copy number variation related to CBL genes. This product achieves the purpose of detection by hybridizing with the CBL gene. Due to this design method, our probe products can detect the amplification and deletion of target genes on chromosomes through FISH. |
| Category: |
Copy Number Variation |
| Probe Kits Volume (µL): |
40 μL |
| Quantity: |
20 Tests |
| Hybridization Solution (µL): |
200 μL |
| Turnaround Time: |
7-10 Business Days |
| Shipping Time: |
1-2 Day Expedited Shipping |
| Storage Conditions: |
Store at -20℃ and avoid light; |
| Shipping Conditions: |
-20℃ |
Gene Details
| Gene Name |
Cbl Proto-oncogene |
| Gene Summary [Provided by RefSeq] |
This gene is a proto-oncogene that encodes a RING finger E3 ubiquitin ligase. The encoded protein is one of the enzymes required for targeting substrates for degradation by the proteasome. This protein mediates the transfer of ubiquitin from ubiquitin conjugating enzymes (E2) to specific substrates. This protein also contains an N-terminal phosphotyrosine binding domain that allows it to interact with numerous tyrosine-phosphorylated substrates and target them for proteasome degradation. As such it functions as a negative regulator of many signal transduction pathways. This gene has been found to be mutated or translocated in many cancers including acute myeloid leukaemia, and expansion of CGG repeats in the 5' UTR has been associated with Jacobsen syndrome. Mutations in this gene are also the cause of Noonan syndrome-like disorder. [provided by RefSeq, Jul 2016] |
| Gene Symbol |
CBL |
| Location |
11q23.3 |
| Chromosome |
Chromosome11 |
| Coordinates |
This gene maps to 119076989-119178859 in GRCh37 coordinates. |
| Species |
Human |
Dye Colors:
OR
RE
GO
GR
AQ
Order Sheet
| Number |
Dye Color |
Order Name |
Absorbance Maximum |
Emission Maximum |
Add to Cart |
| 1 |
OR
|
CNVFP-CBL-01891-OR |
573nm |
548nm |
|
| 2 |
RE
|
CNVFP-CBL-01891-RE |
599nm |
580nm |
|
| 3 |
GO
|
CNVFP-CBL-01891-GO |
551nm |
525nm |
|
| 4 |
GR
|
CNVFP-CBL-01891-GR |
515nm |
491nm |
|
| 5 |
AQ
|
CNVFP-CBL-01891-AQ |
467nm |
418nm |
|
Other Products
