Gene-specific Copy Number Variation Probe-CASP8
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| Catalog: |
CNVFP-CASP8-01939 |
| Classification: |
Copy Number Variation |
| Description: |
Our Gene-specific Copy Number Variation Probes usually target the flanks of the target gene (CASP8). The product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We provide CNV FISH Probes with a variety of dye color combinations to meet various challenges. Probe products not only provide some classic color combinations but also provide customized probe services. |
| Application: |
CASP8 Gene-specific copy number variation probes are mainly used to detect the copy number variation related to CASP8 genes. This product achieves the purpose of detection by hybridizing with the CASP8 gene. Due to this design method, our probe products can detect the amplification and deletion of target genes on chromosomes through FISH. |
| Category: |
Copy Number Variation |
| Probe Kits Volume (µL): |
40 μL |
| Quantity: |
20 Tests |
| Hybridization Solution (µL): |
200 μL |
| Turnaround Time: |
7-10 Business Days |
| Shipping Time: |
1-2 Day Expedited Shipping |
| Storage Conditions: |
Store at -20℃ and avoid light; |
| Shipping Conditions: |
-20℃ |
Gene Details
| Gene Name |
Caspase 8 |
| Gene Summary [Provided by RefSeq] |
This gene encodes a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes composed of a prodomain, a large protease subunit, and a small protease subunit. Activation of caspases requires proteolytic processing at conserved internal aspartic residues to generate a heterodimeric enzyme consisting of the large and small subunits. This protein is involved in the programmed cell death induced by Fas and various apoptotic stimuli. The N-terminal FADD-like death effector domain of this protein suggests that it may interact with Fas-interacting protein FADD. This protein was detected in the insoluble fraction of the affected brain region from Huntington disease patients but not in those from normal controls, which implicated the role in neurodegenerative diseases. Many alternatively spliced transcript variants encoding different isoforms have been described, although not all variants have had their full-length sequences determined. [provided by RefSeq, Jul 2008] |
| Gene Symbol |
CASP8 |
| Location |
2q33.1 |
| Chromosome |
Chromosome2 |
| Coordinates |
This gene maps to 202098165-202152434 in GRCh37 coordinates. |
| Species |
Human |
Dye Colors:
OR
RE
GO
GR
AQ
Order Sheet
| Number |
Dye Color |
Order Name |
Absorbance Maximum |
Emission Maximum |
Add to Cart |
| 1 |
OR
|
CNVFP-CASP8-01939-OR |
573nm |
548nm |
|
| 2 |
RE
|
CNVFP-CASP8-01939-RE |
599nm |
580nm |
|
| 3 |
GO
|
CNVFP-CASP8-01939-GO |
551nm |
525nm |
|
| 4 |
GR
|
CNVFP-CASP8-01939-GR |
515nm |
491nm |
|
| 5 |
AQ
|
CNVFP-CASP8-01939-AQ |
467nm |
418nm |
|
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