Gene-specific Copy Number Variation Probe-C4A
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| Catalog: |
CNVFP-C4A-01693 |
| Classification: |
Copy Number Variation |
| Description: |
Our Gene-specific Copy Number Variation Probes usually target the flanks of the target gene (C4A). The product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We provide CNV FISH Probes with a variety of dye color combinations to meet various challenges. Probe products not only provide some classic color combinations but also provide customized probe services. |
| Application: |
C4A Gene-specific copy number variation probes are mainly used to detect the copy number variation related to C4A genes. This product achieves the purpose of detection by hybridizing with the C4A gene. Due to this design method, our probe products can detect the amplification and deletion of target genes on chromosomes through FISH. |
| Category: |
Copy Number Variation |
| Probe Kits Volume (µL): |
40 μL |
| Quantity: |
20 Tests |
| Hybridization Solution (µL): |
200 μL |
| Turnaround Time: |
7-10 Business Days |
| Shipping Time: |
1-2 Day Expedited Shipping |
| Storage Conditions: |
Store at -20℃ and avoid light; |
| Shipping Conditions: |
-20℃ |
Gene Details
| Gene Name |
Complement C4A (Rodgers Blood Group) |
| Gene Summary [Provided by RefSeq] |
This gene encodes the acidic form of complement factor 4, part of the classical activation pathway. The protein is expressed as a single chain precursor which is proteolytically cleaved into a trimer of alpha, beta, and gamma chains prior to secretion. The trimer provides a surface for interaction between the antigen-antibody complex and other complement components. The alpha chain is cleaved to release C4 anaphylatoxin, an antimicrobial peptide and a mediator of local inflammation. Deficiency of this protein is associated with systemic lupus erythematosus and type I diabetes mellitus. This gene localizes to the major histocompatibility complex (MHC) class III region on chromosome 6. Varying haplotypes of this gene cluster exist, such that individuals may have 1, 2, or 3 copies of this gene. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2014] |
| Gene Symbol |
C4A |
| Location |
6p21.33 |
| Chromosome |
Chromosome6_qbl_hap6 |
| Coordinates |
This gene maps to 3243623-3264248 in GRCh37 coordinates. |
| Species |
Human |
Dye Colors:
OR
RE
GO
GR
AQ
Order Sheet
| Number |
Dye Color |
Order Name |
Absorbance Maximum |
Emission Maximum |
Add to Cart |
| 1 |
OR
|
CNVFP-C4A-01693-OR |
573nm |
548nm |
|
| 2 |
RE
|
CNVFP-C4A-01693-RE |
599nm |
580nm |
|
| 3 |
GO
|
CNVFP-C4A-01693-GO |
551nm |
525nm |
|
| 4 |
GR
|
CNVFP-C4A-01693-GR |
515nm |
491nm |
|
| 5 |
AQ
|
CNVFP-C4A-01693-AQ |
467nm |
418nm |
|
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