Gene-specific Copy Number Variation Probe-BRCC3
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Catalog: |
CNVFP-BRCC3-01592 |
Classification: |
Copy Number Variation |
Description: |
Our Gene-specific Copy Number Variation Probes usually target the flanks of the target gene (BRCC3). The product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We provide CNV FISH Probes with a variety of dye color combinations to meet various challenges. Probe products not only provide some classic color combinations but also provide customized probe services. |
Application: |
BRCC3 Gene-specific copy number variation probes are mainly used to detect the copy number variation related to BRCC3 genes. This product achieves the purpose of detection by hybridizing with the BRCC3 gene. Due to this design method, our probe products can detect the amplification and deletion of target genes on chromosomes through FISH. |
Category: |
Copy Number Variation |
Probe Kits Volume (µL): |
40 μL |
Quantity: |
20 Tests |
Hybridization Solution (µL): |
200 μL |
Turnaround Time: |
7-10 Business Days |
Shipping Time: |
1-2 Day Expedited Shipping |
Storage Conditions: |
Store at -20℃ and avoid light; |
Shipping Conditions: |
-20℃ |
Gene Details
Gene Name |
BRCA1/BRCA2-containing Complex Subunit 3 |
Gene Summary [Provided by RefSeq] |
This gene encodes a subunit of the BRCA1-BRCA2-containing complex (BRCC), which is an E3 ubiquitin ligase. This complex plays a role in the DNA damage response, where it is responsible for the stable accumulation of BRCA1 at DNA break sites. The component encoded by this gene can specifically cleave Lys 63-linked polyubiquitin chains, and it regulates the abundance of these polyubiquitin chains in chromatin. The loss of this gene results in abnormal angiogenesis and is associated with syndromic moyamoya, a cerebrovascular angiopathy. Alternative splicing results in multiple transcript variants. A related pseudogene has been identified on chromosome 5. [provided by RefSeq, Jun 2011] |
Gene Symbol |
BRCC3 |
Location |
Xq28 |
Chromosome |
ChromosomeX |
Coordinates |
This gene maps to 154299694-154351349 in GRCh37 coordinates. |
Species |
Human |
Dye Colors:
OR
RE
GO
GR
AQ
Order Sheet
Number |
Dye Color |
Order Name |
Absorbance Maximum |
Emission Maximum |
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1 |
OR
|
CNVFP-BRCC3-01592-OR |
573nm |
548nm |
|
2 |
RE
|
CNVFP-BRCC3-01592-RE |
599nm |
580nm |
|
3 |
GO
|
CNVFP-BRCC3-01592-GO |
551nm |
525nm |
|
4 |
GR
|
CNVFP-BRCC3-01592-GR |
515nm |
491nm |
|
5 |
AQ
|
CNVFP-BRCC3-01592-AQ |
467nm |
418nm |
|
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