Gene-specific Copy Number Variation Probe-BARD1
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| Catalog: |
CNVFP-BARD1-01469 |
| Classification: |
Copy Number Variation |
| Description: |
Our Gene-specific Copy Number Variation Probes usually target the flanks of the target gene (BARD1). The product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We provide CNV FISH Probes with a variety of dye color combinations to meet various challenges. Probe products not only provide some classic color combinations but also provide customized probe services. |
| Application: |
BARD1 Gene-specific copy number variation probes are mainly used to detect the copy number variation related to BARD1 genes. This product achieves the purpose of detection by hybridizing with the BARD1 gene. Due to this design method, our probe products can detect the amplification and deletion of target genes on chromosomes through FISH. |
| Category: |
Copy Number Variation |
| Probe Kits Volume (µL): |
40 μL |
| Quantity: |
20 Tests |
| Hybridization Solution (µL): |
200 μL |
| Turnaround Time: |
7-10 Business Days |
| Shipping Time: |
1-2 Day Expedited Shipping |
| Storage Conditions: |
Store at -20℃ and avoid light; |
| Shipping Conditions: |
-20℃ |
Gene Details
| Gene Name |
BRCA1 Associated RING Domain 1 |
| Gene Summary [Provided by RefSeq] |
This gene encodes a protein which interacts with the N-terminal region of BRCA1. In addition to its ability to bind BRCA1 in vivo and in vitro, it shares homology with the 2 most conserved regions of BRCA1: the N-terminal RING motif and the C-terminal BRCT domain. The RING motif is a cysteine-rich sequence found in a variety of proteins that regulate cell growth, including the products of tumor suppressor genes and dominant protooncogenes. This protein also contains 3 tandem ankyrin repeats. The BARD1/BRCA1 interaction is disrupted by tumorigenic amino acid substitutions in BRCA1, implying that the formation of a stable complex between these proteins may be an essential aspect of BRCA1 tumor suppression. This protein may be the target of oncogenic mutations in breast or ovarian cancer. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2013] |
| Gene Symbol |
BARD1 |
| Location |
2q35 |
| Chromosome |
Chromosome2 |
| Coordinates |
This gene maps to 215593274-215674428 in GRCh37 coordinates. |
| Species |
Human |
Dye Colors:
OR
RE
GO
GR
AQ
Order Sheet
| Number |
Dye Color |
Order Name |
Absorbance Maximum |
Emission Maximum |
Add to Cart |
| 1 |
OR
|
CNVFP-BARD1-01469-OR |
573nm |
548nm |
|
| 2 |
RE
|
CNVFP-BARD1-01469-RE |
599nm |
580nm |
|
| 3 |
GO
|
CNVFP-BARD1-01469-GO |
551nm |
525nm |
|
| 4 |
GR
|
CNVFP-BARD1-01469-GR |
515nm |
491nm |
|
| 5 |
AQ
|
CNVFP-BARD1-01469-AQ |
467nm |
418nm |
|
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