Gene-specific Copy Number Variation Probe-BAG4
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Catalog: |
CNVFP-BAG4-01488 |
Classification: |
Copy Number Variation |
Description: |
Our Gene-specific Copy Number Variation Probes usually target the flanks of the target gene (BAG4). The product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We provide CNV FISH Probes with a variety of dye color combinations to meet various challenges. Probe products not only provide some classic color combinations but also provide customized probe services. |
Application: |
BAG4 Gene-specific copy number variation probes are mainly used to detect the copy number variation related to BAG4 genes. This product achieves the purpose of detection by hybridizing with the BAG4 gene. Due to this design method, our probe products can detect the amplification and deletion of target genes on chromosomes through FISH. |
Category: |
Copy Number Variation |
Probe Kits Volume (µL): |
40 μL |
Quantity: |
20 Tests |
Hybridization Solution (µL): |
200 μL |
Turnaround Time: |
7-10 Business Days |
Shipping Time: |
1-2 Day Expedited Shipping |
Storage Conditions: |
Store at -20℃ and avoid light; |
Shipping Conditions: |
-20℃ |
Gene Details
Gene Name |
BCL2 Associated Athanogene 4 |
Gene Summary [Provided by RefSeq] |
The protein encoded by this gene is a member of the BAG1-related protein family. BAG1 is an anti-apoptotic protein that functions through interactions with a variety of cell apoptosis and growth related proteins including BCL-2, Raf-protein kinase, steroid hormone receptors, growth factor receptors and members of the heat shock protein 70 kDa family. This protein contains a BAG domain near the C-terminus, which could bind and inhibit the chaperone activity of Hsc70/Hsp70. This protein was found to be associated with the death domain of tumor necrosis factor receptor type 1 (TNF-R1) and death receptor-3 (DR3), and thereby negatively regulates downstream cell death signaling. The regulatory role of this protein in cell death was demonstrated in epithelial cells which undergo apoptosis while integrin mediated matrix contacts are lost. Alternatively spliced transcript variants encoding distinct isoforms have been identified. [provided by RefSeq, Mar 2011] |
Gene Symbol |
BAG4 |
Location |
8p11.23 |
Chromosome |
Chromosome8 |
Coordinates |
This gene maps to 38034105-38070819 in GRCh37 coordinates. |
Species |
Human |
Dye Colors:
OR
RE
GO
GR
AQ
Order Sheet
Number |
Dye Color |
Order Name |
Absorbance Maximum |
Emission Maximum |
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1 |
OR
|
CNVFP-BAG4-01488-OR |
573nm |
548nm |
|
2 |
RE
|
CNVFP-BAG4-01488-RE |
599nm |
580nm |
|
3 |
GO
|
CNVFP-BAG4-01488-GO |
551nm |
525nm |
|
4 |
GR
|
CNVFP-BAG4-01488-GR |
515nm |
491nm |
|
5 |
AQ
|
CNVFP-BAG4-01488-AQ |
467nm |
418nm |
|
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