Gene-specific Copy Number Variation Probe-AXIN2
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| Catalog: |
CNVFP-AXIN2-01158 |
| Classification: |
Copy Number Variation |
| Description: |
Our Gene-specific Copy Number Variation Probes usually target the flanks of the target gene (AXIN2). The product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We provide CNV FISH Probes with a variety of dye color combinations to meet various challenges. Probe products not only provide some classic color combinations but also provide customized probe services. |
| Application: |
AXIN2 Gene-specific copy number variation probes are mainly used to detect the copy number variation related to AXIN2 genes. This product achieves the purpose of detection by hybridizing with the AXIN2 gene. Due to this design method, our probe products can detect the amplification and deletion of target genes on chromosomes through FISH. |
| Category: |
Copy Number Variation |
| Probe Kits Volume (µL): |
40 μL |
| Quantity: |
20 Tests |
| Hybridization Solution (µL): |
200 μL |
| Turnaround Time: |
7-10 Business Days |
| Shipping Time: |
1-2 Day Expedited Shipping |
| Storage Conditions: |
Store at -20℃ and avoid light; |
| Shipping Conditions: |
-20℃ |
Gene Details
| Gene Name |
Axin 2 |
| Gene Summary [Provided by RefSeq] |
The Axin-related protein, Axin2, presumably plays an important role in the regulation of the stability of beta-catenin in the Wnt signaling pathway, like its rodent homologs, mouse conductin/rat axil. In mouse, conductin organizes a multiprotein complex of APC (adenomatous polyposis of the colon), beta-catenin, glycogen synthase kinase 3-beta, and conductin, which leads to the degradation of beta-catenin. Apparently, the deregulation of beta-catenin is an important event in the genesis of a number of malignancies. The AXIN2 gene has been mapped to 17q23-q24, a region that shows frequent loss of heterozygosity in breast cancer, neuroblastoma, and other tumors. Mutations in this gene have been associated with colorectal cancer with defective mismatch repair. [provided by RefSeq, Jul 2008] |
| Gene Symbol |
AXIN2 |
| Location |
17q24.1 |
| Chromosome |
Chromosome17 |
| Coordinates |
This gene maps to 63524682-63557740 in GRCh37 coordinates. |
| Species |
Human |
Dye Colors:
OR
RE
GO
GR
AQ
Order Sheet
| Number |
Dye Color |
Order Name |
Absorbance Maximum |
Emission Maximum |
Add to Cart |
| 1 |
OR
|
CNVFP-AXIN2-01158-OR |
573nm |
548nm |
|
| 2 |
RE
|
CNVFP-AXIN2-01158-RE |
599nm |
580nm |
|
| 3 |
GO
|
CNVFP-AXIN2-01158-GO |
551nm |
525nm |
|
| 4 |
GR
|
CNVFP-AXIN2-01158-GR |
515nm |
491nm |
|
| 5 |
AQ
|
CNVFP-AXIN2-01158-AQ |
467nm |
418nm |
|
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