Gene-specific Copy Number Variation Probe-ASAP2
Add to Cart
| Catalog: |
CNVFP-ASAP2-00972 |
| Classification: |
Copy Number Variation |
| Description: |
Our Gene-specific Copy Number Variation Probes usually target the flanks of the target gene (ASAP2). The product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We provide CNV FISH Probes with a variety of dye color combinations to meet various challenges. Probe products not only provide some classic color combinations but also provide customized probe services. |
| Application: |
ASAP2 Gene-specific copy number variation probes are mainly used to detect the copy number variation related to ASAP2 genes. This product achieves the purpose of detection by hybridizing with the ASAP2 gene. Due to this design method, our probe products can detect the amplification and deletion of target genes on chromosomes through FISH. |
| Category: |
Copy Number Variation |
| Probe Kits Volume (µL): |
40 μL |
| Quantity: |
20 Tests |
| Hybridization Solution (µL): |
200 μL |
| Turnaround Time: |
7-10 Business Days |
| Shipping Time: |
1-2 Day Expedited Shipping |
| Storage Conditions: |
Store at -20℃ and avoid light; |
| Shipping Conditions: |
-20℃ |
Gene Details
| Gene Name |
ArfGAP With SH3 Domain, Ankyrin Repeat And PH Domain 2 |
| Gene Summary [Provided by RefSeq] |
This gene encodes a multidomain protein containing an N-terminal alpha-helical region with a coiled-coil motif, followed by a pleckstrin homology (PH) domain, an Arf-GAP domain, an ankyrin homology region, a proline-rich region, and a C-terminal Src homology 3 (SH3) domain. The protein localizes in the Golgi apparatus and at the plasma membrane, where it colocalizes with protein tyrosine kinase 2-beta (PYK2). The encoded protein forms a stable complex with PYK2 in vivo. This interaction appears to be mediated by binding of its SH3 domain to the C-terminal proline-rich domain of PYK2. The encoded protein is tyrosine phosphorylated by activated PYK2. It has catalytic activity for class I and II ArfGAPs in vitro, and can bind the class III Arf ARF6 without immediate GAP activity. The encoded protein is believed to function as an ARF GAP that controls ARF-mediated vesicle budding when recruited to Golgi membranes. In addition, it functions as a substrate and downstream target for PYK2 and SRC, a pathway that may be involved in the regulation of vesicular transport. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2008] |
| Gene Symbol |
ASAP2 |
| Location |
2p24 |
| Chromosome |
Chromosome2 |
| Coordinates |
This gene maps to 9346893-9545812 in GRCh37 coordinates. |
| Species |
Human |
Dye Colors:
OR
RE
GO
GR
AQ
Order Sheet
| Number |
Dye Color |
Order Name |
Absorbance Maximum |
Emission Maximum |
Add to Cart |
| 1 |
OR
|
CNVFP-ASAP2-00972-OR |
573nm |
548nm |
|
| 2 |
RE
|
CNVFP-ASAP2-00972-RE |
599nm |
580nm |
|
| 3 |
GO
|
CNVFP-ASAP2-00972-GO |
551nm |
525nm |
|
| 4 |
GR
|
CNVFP-ASAP2-00972-GR |
515nm |
491nm |
|
| 5 |
AQ
|
CNVFP-ASAP2-00972-AQ |
467nm |
418nm |
|
Other Products
