Gene-specific Copy Number Variation Probe-AR
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| Catalog: |
CNVFP-AR-00792 |
| Classification: |
Copy Number Variation |
| Description: |
Our Gene-specific Copy Number Variation Probes usually target the flanks of the target gene (AR). The product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We provide CNV FISH Probes with a variety of dye color combinations to meet various challenges. Probe products not only provide some classic color combinations but also provide customized probe services. |
| Application: |
AR Gene-specific copy number variation probes are mainly used to detect the copy number variation related to AR genes. This product achieves the purpose of detection by hybridizing with the AR gene. Due to this design method, our probe products can detect the amplification and deletion of target genes on chromosomes through FISH. |
| Category: |
Copy Number Variation |
| Probe Kits Volume (µL): |
40 μL |
| Quantity: |
20 Tests |
| Hybridization Solution (µL): |
200 μL |
| Turnaround Time: |
7-10 Business Days |
| Shipping Time: |
1-2 Day Expedited Shipping |
| Storage Conditions: |
Store at -20℃ and avoid light; |
| Shipping Conditions: |
-20℃ |
Gene Details
| Gene Name |
Androgen Receptor |
| Gene Summary [Provided by RefSeq] |
The androgen receptor gene is more than 90 kb long and codes for a protein that has 3 major functional domains: the N-terminal domain, DNA-binding domain, and androgen-binding domain. The protein functions as a steroid-hormone activated transcription factor. Upon binding the hormone ligand, the receptor dissociates from accessory proteins, translocates into the nucleus, dimerizes, and then stimulates transcription of androgen responsive genes. This gene contains 2 polymorphic trinucleotide repeat segments that encode polyglutamine and polyglycine tracts in the N-terminal transactivation domain of its protein. Expansion of the polyglutamine tract from the normal 9-34 repeats to the pathogenic 38-62 repeats causes spinal bulbar muscular atrophy (SBMA, also known as Kennedy's disease). Mutations in this gene are also associated with complete androgen insensitivity (CAIS). Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jan 2017] |
| Gene Symbol |
AR |
| Location |
Xq12 |
| Chromosome |
ChromosomeX |
| Coordinates |
This gene maps to 66763873-66944119 in GRCh37 coordinates. |
| Species |
Human |
Dye Colors:
OR
RE
GO
GR
AQ
Order Sheet
| Number |
Dye Color |
Order Name |
Absorbance Maximum |
Emission Maximum |
Add to Cart |
| 1 |
OR
|
CNVFP-AR-00792-OR |
573nm |
548nm |
|
| 2 |
RE
|
CNVFP-AR-00792-RE |
599nm |
580nm |
|
| 3 |
GO
|
CNVFP-AR-00792-GO |
551nm |
525nm |
|
| 4 |
GR
|
CNVFP-AR-00792-GR |
515nm |
491nm |
|
| 5 |
AQ
|
CNVFP-AR-00792-AQ |
467nm |
418nm |
|
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