Gene-specific Copy Number Variation Probe-APP
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| Catalog: |
CNVFP-APP-00753 |
| Classification: |
Copy Number Variation |
| Description: |
Our Gene-specific Copy Number Variation Probes usually target the flanks of the target gene (APP). The product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We provide CNV FISH Probes with a variety of dye color combinations to meet various challenges. Probe products not only provide some classic color combinations but also provide customized probe services. |
| Application: |
APP Gene-specific copy number variation probes are mainly used to detect the copy number variation related to APP genes. This product achieves the purpose of detection by hybridizing with the APP gene. Due to this design method, our probe products can detect the amplification and deletion of target genes on chromosomes through FISH. |
| Category: |
Copy Number Variation |
| Probe Kits Volume (µL): |
40 μL |
| Quantity: |
20 Tests |
| Hybridization Solution (µL): |
200 μL |
| Turnaround Time: |
7-10 Business Days |
| Shipping Time: |
1-2 Day Expedited Shipping |
| Storage Conditions: |
Store at -20℃ and avoid light; |
| Shipping Conditions: |
-20℃ |
Gene Details
| Gene Name |
Amyloid Beta Precursor Protein |
| Gene Summary [Provided by RefSeq] |
This gene encodes a cell surface receptor and transmembrane precursor protein that is cleaved by secretases to form a number of peptides. Some of these peptides are secreted and can bind to the acetyltransferase complex APBB1/TIP60 to promote transcriptional activation, while others form the protein basis of the amyloid plaques found in the brains of patients with Alzheimer disease. In addition, two of the peptides are antimicrobial peptides, having been shown to have bacteriocidal and antifungal activities. Mutations in this gene have been implicated in autosomal dominant Alzheimer disease and cerebroarterial amyloidosis (cerebral amyloid angiopathy). Multiple transcript variants encoding several different isoforms have been found for this gene. [provided by RefSeq, Aug 2014] |
| Gene Symbol |
APP |
| Location |
21q21.3 |
| Chromosome |
Chromosome21 |
| Coordinates |
This gene maps to 27252860-27543446 in GRCh37 coordinates. |
| Species |
Human |
Dye Colors:
OR
RE
GO
GR
AQ
Order Sheet
| Number |
Dye Color |
Order Name |
Absorbance Maximum |
Emission Maximum |
Add to Cart |
| 1 |
OR
|
CNVFP-APP-00753-OR |
573nm |
548nm |
|
| 2 |
RE
|
CNVFP-APP-00753-RE |
599nm |
580nm |
|
| 3 |
GO
|
CNVFP-APP-00753-GO |
551nm |
525nm |
|
| 4 |
GR
|
CNVFP-APP-00753-GR |
515nm |
491nm |
|
| 5 |
AQ
|
CNVFP-APP-00753-AQ |
467nm |
418nm |
|
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