Gene-specific Copy Number Variation Probe-APOB
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| Catalog: |
CNVFP-APOB-00889 |
| Classification: |
Copy Number Variation |
| Description: |
Our Gene-specific Copy Number Variation Probes usually target the flanks of the target gene (APOB). The product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We provide CNV FISH Probes with a variety of dye color combinations to meet various challenges. Probe products not only provide some classic color combinations but also provide customized probe services. |
| Application: |
APOB Gene-specific copy number variation probes are mainly used to detect the copy number variation related to APOB genes. This product achieves the purpose of detection by hybridizing with the APOB gene. Due to this design method, our probe products can detect the amplification and deletion of target genes on chromosomes through FISH. |
| Category: |
Copy Number Variation |
| Probe Kits Volume (µL): |
40 μL |
| Quantity: |
20 Tests |
| Hybridization Solution (µL): |
200 μL |
| Turnaround Time: |
7-10 Business Days |
| Shipping Time: |
1-2 Day Expedited Shipping |
| Storage Conditions: |
Store at -20℃ and avoid light; |
| Shipping Conditions: |
-20℃ |
Gene Details
| Gene Name |
Apolipoprotein B |
| Gene Summary [Provided by RefSeq] |
This gene product is the main apolipoprotein of chylomicrons and low density lipoproteins. It occurs in plasma as two main isoforms, apoB-48 and apoB-100: the former is synthesized exclusively in the gut and the latter in the liver. The intestinal and the hepatic forms of apoB are encoded by a single gene from a single, very long mRNA. The two isoforms share a common N-terminal sequence. The shorter apoB-48 protein is produced after RNA editing of the apoB-100 transcript at residue 2180 (CAA->UAA), resulting in the creation of a stop codon, and early translation termination. Mutations in this gene or its regulatory region cause hypobetalipoproteinemia, normotriglyceridemic hypobetalipoproteinemia, and hypercholesterolemia due to ligand-defective apoB, diseases affecting plasma cholesterol and apoB levels. [provided by RefSeq, Jul 2008] |
| Gene Symbol |
APOB |
| Location |
2p24.1 |
| Chromosome |
Chromosome2 |
| Coordinates |
This gene maps to 21224300-21266945 in GRCh37 coordinates. |
| Species |
Human |
Dye Colors:
OR
RE
GO
GR
AQ
Order Sheet
| Number |
Dye Color |
Order Name |
Absorbance Maximum |
Emission Maximum |
Add to Cart |
| 1 |
OR
|
CNVFP-APOB-00889-OR |
573nm |
548nm |
|
| 2 |
RE
|
CNVFP-APOB-00889-RE |
599nm |
580nm |
|
| 3 |
GO
|
CNVFP-APOB-00889-GO |
551nm |
525nm |
|
| 4 |
GR
|
CNVFP-APOB-00889-GR |
515nm |
491nm |
|
| 5 |
AQ
|
CNVFP-APOB-00889-AQ |
467nm |
418nm |
|
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