Gene-specific Copy Number Variation Probe-APH1A
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| Catalog: |
CNVFP-APH1A-00871 |
| Classification: |
Copy Number Variation |
| Description: |
Our Gene-specific Copy Number Variation Probes usually target the flanks of the target gene (APH1A). The product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We provide CNV FISH Probes with a variety of dye color combinations to meet various challenges. Probe products not only provide some classic color combinations but also provide customized probe services. |
| Application: |
APH1A Gene-specific copy number variation probes are mainly used to detect the copy number variation related to APH1A genes. This product achieves the purpose of detection by hybridizing with the APH1A gene. Due to this design method, our probe products can detect the amplification and deletion of target genes on chromosomes through FISH. |
| Category: |
Copy Number Variation |
| Probe Kits Volume (µL): |
40 μL |
| Quantity: |
20 Tests |
| Hybridization Solution (µL): |
200 μL |
| Turnaround Time: |
7-10 Business Days |
| Shipping Time: |
1-2 Day Expedited Shipping |
| Storage Conditions: |
Store at -20℃ and avoid light; |
| Shipping Conditions: |
-20℃ |
Gene Details
| Gene Name |
Aph-1 Homolog A, Gamma-secretase Subunit |
| Gene Summary [Provided by RefSeq] |
This gene encodes a component of the gamma secretase complex that cleaves integral membrane proteins such as Notch receptors and beta-amyloid precursor protein. The gamma secretase complex contains this gene product, or the paralogous anterior pharynx defective 1 homolog B (APH1B), along with the presenilin, nicastrin, and presenilin enhancer-2 proteins. The precise function of this seven-transmembrane-domain protein is unknown though it is suspected of facilitating the association of nicastrin and presenilin in the gamma secretase complex as well as interacting with substrates of the gamma secretase complex prior to their proteolytic processing. Polymorphisms in a promoter region of this gene have been associated with an increased risk for developing sporadic Alzheimer's disease. Alternative splicing results in multiple protein-coding and non-protein-coding transcript variants. [provided by RefSeq, Aug 2011] |
| Gene Symbol |
APH1A |
| Location |
1q21.2 |
| Chromosome |
Chromosome1 |
| Coordinates |
This gene maps to 150237798-150241609 in GRCh37 coordinates. |
| Species |
Human |
Dye Colors:
OR
RE
GO
GR
AQ
Order Sheet
| Number |
Dye Color |
Order Name |
Absorbance Maximum |
Emission Maximum |
Add to Cart |
| 1 |
OR
|
CNVFP-APH1A-00871-OR |
573nm |
548nm |
|
| 2 |
RE
|
CNVFP-APH1A-00871-RE |
599nm |
580nm |
|
| 3 |
GO
|
CNVFP-APH1A-00871-GO |
551nm |
525nm |
|
| 4 |
GR
|
CNVFP-APH1A-00871-GR |
515nm |
491nm |
|
| 5 |
AQ
|
CNVFP-APH1A-00871-AQ |
467nm |
418nm |
|
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