Gene-specific Copy Number Variation Probe-ANK1
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| Catalog: |
CNVFP-ANK1-00493 |
| Classification: |
Copy Number Variation |
| Description: |
Our Gene-specific Copy Number Variation Probes usually target the flanks of the target gene (ANK1). The product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We provide CNV FISH Probes with a variety of dye color combinations to meet various challenges. Probe products not only provide some classic color combinations but also provide customized probe services. |
| Application: |
ANK1 Gene-specific copy number variation probes are mainly used to detect the copy number variation related to ANK1 genes. This product achieves the purpose of detection by hybridizing with the ANK1 gene. Due to this design method, our probe products can detect the amplification and deletion of target genes on chromosomes through FISH. |
| Category: |
Copy Number Variation |
| Probe Kits Volume (µL): |
40 μL |
| Quantity: |
20 Tests |
| Hybridization Solution (µL): |
200 μL |
| Turnaround Time: |
7-10 Business Days |
| Shipping Time: |
1-2 Day Expedited Shipping |
| Storage Conditions: |
Store at -20℃ and avoid light; |
| Shipping Conditions: |
-20℃ |
Gene Details
| Gene Name |
Ankyrin 1 |
| Gene Summary [Provided by RefSeq] |
Ankyrins are a family of proteins that link the integral membrane proteins to the underlying spectrin-actin cytoskeleton and play key roles in activities such as cell motility, activation, proliferation, contact and the maintenance of specialized membrane domains. Multiple isoforms of ankyrin with different affinities for various target proteins are expressed in a tissue-specific, developmentally regulated manner. Most ankyrins are typically composed of three structural domains: an amino-terminal domain containing multiple ankyrin repeats; a central region with a highly conserved spectrin binding domain; and a carboxy-terminal regulatory domain which is the least conserved and subject to variation. Ankyrin 1, the prototype of this family, was first discovered in the erythrocytes, but since has also been found in brain and muscles. Mutations in erythrocytic ankyrin 1 have been associated in approximately half of all patients with hereditary spherocytosis. Complex patterns of alternative splicing in the regulatory domain, giving rise to different isoforms of ankyrin 1 have been described. Truncated muscle-specific isoforms of ankyrin 1 resulting from usage of an alternate promoter have also been identified. [provided by RefSeq, Dec 2008] |
| Gene Symbol |
ANK1 |
| Location |
8p11.21 |
| Chromosome |
Chromosome8 |
| Coordinates |
This gene maps to 41510743-41754280 in GRCh37 coordinates. |
| Species |
Human |
Dye Colors:
OR
RE
GO
GR
AQ
Order Sheet
| Number |
Dye Color |
Order Name |
Absorbance Maximum |
Emission Maximum |
Add to Cart |
| 1 |
OR
|
CNVFP-ANK1-00493-OR |
573nm |
548nm |
|
| 2 |
RE
|
CNVFP-ANK1-00493-RE |
599nm |
580nm |
|
| 3 |
GO
|
CNVFP-ANK1-00493-GO |
551nm |
525nm |
|
| 4 |
GR
|
CNVFP-ANK1-00493-GR |
515nm |
491nm |
|
| 5 |
AQ
|
CNVFP-ANK1-00493-AQ |
467nm |
418nm |
|
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