Gene-specific Copy Number Variation Probe-ALOX5
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| Catalog: |
CNVFP-ALOX5-00546 |
| Classification: |
Copy Number Variation |
| Description: |
Our Gene-specific Copy Number Variation Probes usually target the flanks of the target gene (ALOX5). The product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We provide CNV FISH Probes with a variety of dye color combinations to meet various challenges. Probe products not only provide some classic color combinations but also provide customized probe services. |
| Application: |
ALOX5 Gene-specific copy number variation probes are mainly used to detect the copy number variation related to ALOX5 genes. This product achieves the purpose of detection by hybridizing with the ALOX5 gene. Due to this design method, our probe products can detect the amplification and deletion of target genes on chromosomes through FISH. |
| Category: |
Copy Number Variation |
| Probe Kits Volume (µL): |
40 μL |
| Quantity: |
20 Tests |
| Hybridization Solution (µL): |
200 μL |
| Turnaround Time: |
7-10 Business Days |
| Shipping Time: |
1-2 Day Expedited Shipping |
| Storage Conditions: |
Store at -20℃ and avoid light; |
| Shipping Conditions: |
-20℃ |
Gene Details
| Gene Name |
Arachidonate 5-lipoxygenase |
| Gene Summary [Provided by RefSeq] |
This gene encodes a member of the lipoxygenase gene family and plays a dual role in the synthesis of leukotrienes from arachidonic acid. The encoded protein, which is expressed specifically in bone marrow-derived cells, catalyzes the conversion of arachidonic acid to 5(S)-hydroperoxy-6-trans-8,11,14-cis-eicosatetraenoic acid, and further to the allylic epoxide 5(S)-trans-7,9-trans-11,14-cis-eicosatetrenoic acid (leukotriene A4). Leukotrienes are important mediators of a number of inflammatory and allergic conditions. Mutations in the promoter region of this gene lead to a diminished response to antileukotriene drugs used in the treatment of asthma and may also be associated with atherosclerosis and several cancers. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2012] |
| Gene Symbol |
ALOX5 |
| Location |
10q11.21 |
| Chromosome |
Chromosome10 |
| Coordinates |
This gene maps to 45869628-45941563 in GRCh37 coordinates. |
| Species |
Human |
Dye Colors:
OR
RE
GO
GR
AQ
Order Sheet
| Number |
Dye Color |
Order Name |
Absorbance Maximum |
Emission Maximum |
Add to Cart |
| 1 |
OR
|
CNVFP-ALOX5-00546-OR |
573nm |
548nm |
|
| 2 |
RE
|
CNVFP-ALOX5-00546-RE |
599nm |
580nm |
|
| 3 |
GO
|
CNVFP-ALOX5-00546-GO |
551nm |
525nm |
|
| 4 |
GR
|
CNVFP-ALOX5-00546-GR |
515nm |
491nm |
|
| 5 |
AQ
|
CNVFP-ALOX5-00546-AQ |
467nm |
418nm |
|
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