Gene-specific Copy Number Variation Probe-ALDH2
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| Catalog: |
CNVFP-ALDH2-00600 |
| Classification: |
Copy Number Variation |
| Description: |
Our Gene-specific Copy Number Variation Probes usually target the flanks of the target gene (ALDH2). The product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We provide CNV FISH Probes with a variety of dye color combinations to meet various challenges. Probe products not only provide some classic color combinations but also provide customized probe services. |
| Application: |
ALDH2 Gene-specific copy number variation probes are mainly used to detect the copy number variation related to ALDH2 genes. This product achieves the purpose of detection by hybridizing with the ALDH2 gene. Due to this design method, our probe products can detect the amplification and deletion of target genes on chromosomes through FISH. |
| Category: |
Copy Number Variation |
| Probe Kits Volume (µL): |
40 μL |
| Quantity: |
20 Tests |
| Hybridization Solution (µL): |
200 μL |
| Turnaround Time: |
7-10 Business Days |
| Shipping Time: |
1-2 Day Expedited Shipping |
| Storage Conditions: |
Store at -20℃ and avoid light; |
| Shipping Conditions: |
-20℃ |
Gene Details
| Gene Name |
Aldehyde Dehydrogenase 2 Family (mitochondrial) |
| Gene Summary [Provided by RefSeq] |
This protein belongs to the aldehyde dehydrogenase family of proteins. Aldehyde dehydrogenase is the second enzyme of the major oxidative pathway of alcohol metabolism. Two major liver isoforms of aldehyde dehydrogenase, cytosolic and mitochondrial, can be distinguished by their electrophoretic mobilities, kinetic properties, and subcellular localizations. Most Caucasians have two major isozymes, while approximately 50% of East Asians have the cytosolic isozyme but not the mitochondrial isozyme. A remarkably higher frequency of acute alcohol intoxication among East Asians than among Caucasians could be related to the absence of a catalytically active form of the mitochondrial isozyme. The increased exposure to acetaldehyde in individuals with the catalytically inactive form may also confer greater susceptibility to many types of cancer. This gene encodes a mitochondrial isoform, which has a low Km for acetaldehydes, and is localized in mitochondrial matrix. Alternative splicing results in multiple transcript variants encoding distinct isoforms.[provided by RefSeq, Nov 2016] |
| Gene Symbol |
ALDH2 |
| Location |
12q24.12 |
| Chromosome |
Chromosome12 |
| Coordinates |
This gene maps to 112204690-112247789 in GRCh37 coordinates. |
| Species |
Human |
Dye Colors:
OR
RE
GO
GR
AQ
Order Sheet
| Number |
Dye Color |
Order Name |
Absorbance Maximum |
Emission Maximum |
Add to Cart |
| 1 |
OR
|
CNVFP-ALDH2-00600-OR |
573nm |
548nm |
|
| 2 |
RE
|
CNVFP-ALDH2-00600-RE |
599nm |
580nm |
|
| 3 |
GO
|
CNVFP-ALDH2-00600-GO |
551nm |
525nm |
|
| 4 |
GR
|
CNVFP-ALDH2-00600-GR |
515nm |
491nm |
|
| 5 |
AQ
|
CNVFP-ALDH2-00600-AQ |
467nm |
418nm |
|
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