Gene-specific Copy Number Variation Probe-AFF1
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| Catalog: |
CNVFP-AFF1-00389 |
| Classification: |
Copy Number Variation |
| Description: |
Our Gene-specific Copy Number Variation Probes usually target the flanks of the target gene (AFF1). The product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We provide CNV FISH Probes with a variety of dye color combinations to meet various challenges. Probe products not only provide some classic color combinations but also provide customized probe services. |
| Application: |
AFF1 Gene-specific copy number variation probes are mainly used to detect the copy number variation related to AFF1 genes. This product achieves the purpose of detection by hybridizing with the AFF1 gene. Due to this design method, our probe products can detect the amplification and deletion of target genes on chromosomes through FISH. |
| Category: |
Copy Number Variation |
| Probe Kits Volume (µL): |
40 μL |
| Quantity: |
20 Tests |
| Hybridization Solution (µL): |
200 μL |
| Turnaround Time: |
7-10 Business Days |
| Shipping Time: |
1-2 Day Expedited Shipping |
| Storage Conditions: |
Store at -20℃ and avoid light; |
| Shipping Conditions: |
-20℃ |
Gene Details
| Gene Name |
AF4/FMR2 Family Member 1 |
| Gene Summary [Provided by RefSeq] |
This gene encodes a member of the AF4/ lymphoid nuclear protein related to the Fragile X E syndrome (FRAXE) family of proteins, which have been implicated in human childhood lymphoblastic leukemia, fragile chromosome X intellectual disability, and ataxia. It is the prevalent mixed-lineage leukemia fusion gene associated with spontaneous acute lymphoblastic leukemia. Members of this family have three conserved domains: an N-terminal homology domain, an AF4/ lymphoid nuclear protein domain, and a C-terminal homology domain. The protein functions as a regulator of RNA polymerase II-mediated transcription through elongation and chromatin remodeling functions. Through RNA interference screens, this gene has been shown to promote the expression of CD133, a plasma membrane glycoprotein required for leukemia cell survival. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2017] |
| Gene Symbol |
AFF1 |
| Location |
4q21.3-q22.1 |
| Chromosome |
Chromosome4 |
| Coordinates |
This gene maps to 87856153-88062206 in GRCh37 coordinates. |
| Species |
Human |
Dye Colors:
OR
RE
GO
GR
AQ
Order Sheet
| Number |
Dye Color |
Order Name |
Absorbance Maximum |
Emission Maximum |
Add to Cart |
| 1 |
OR
|
CNVFP-AFF1-00389-OR |
573nm |
548nm |
|
| 2 |
RE
|
CNVFP-AFF1-00389-RE |
599nm |
580nm |
|
| 3 |
GO
|
CNVFP-AFF1-00389-GO |
551nm |
525nm |
|
| 4 |
GR
|
CNVFP-AFF1-00389-GR |
515nm |
491nm |
|
| 5 |
AQ
|
CNVFP-AFF1-00389-AQ |
467nm |
418nm |
|
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