Gene-specific Copy Number Variation Probe-ADAMTS4
Add to Cart
| Catalog: |
CNVFP-ADAMTS4-00075 |
| Classification: |
Copy Number Variation |
| Description: |
Our Gene-specific Copy Number Variation Probes usually target the flanks of the target gene (ADAMTS4). The product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We provide CNV FISH Probes with a variety of dye color combinations to meet various challenges. Probe products not only provide some classic color combinations but also provide customized probe services. |
| Application: |
ADAMTS4 Gene-specific copy number variation probes are mainly used to detect the copy number variation related to ADAMTS4 genes. This product achieves the purpose of detection by hybridizing with the ADAMTS4 gene. Due to this design method, our probe products can detect the amplification and deletion of target genes on chromosomes through FISH. |
| Category: |
Copy Number Variation |
| Probe Kits Volume (µL): |
40 μL |
| Quantity: |
20 Tests |
| Hybridization Solution (µL): |
200 μL |
| Turnaround Time: |
7-10 Business Days |
| Shipping Time: |
1-2 Day Expedited Shipping |
| Storage Conditions: |
Store at -20℃ and avoid light; |
| Shipping Conditions: |
-20℃ |
Gene Details
| Gene Name |
ADAM Metallopeptidase With Thrombospondin Type 1 Motif 4 |
| Gene Summary [Provided by RefSeq] |
This gene encodes a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) protein family. Members of this family share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. The enzyme encoded by this gene lacks a C-terminal TS motif. The encoded preproprotein is proteolytically processed to generate the mature protease. This protease is responsible for the degradation of aggrecan, a major proteoglycan of cartilage, and brevican, a brain-specific extracellular matrix protein. The expression of this gene is upregulated in arthritic disease and this may contribute to disease progression through the degradation of aggrecan. Alternative splicing results in multiple transcript variants, at least one of which encodes an isoform that is proteolytically processed. [provided by RefSeq, Feb 2016] |
| Gene Symbol |
ADAMTS4 |
| Location |
1q23.3 |
| Chromosome |
Chromosome1 |
| Coordinates |
This gene maps to 161159537-161168845 in GRCh37 coordinates. |
| Species |
Human |
Dye Colors:
OR
RE
GO
GR
AQ
Order Sheet
| Number |
Dye Color |
Order Name |
Absorbance Maximum |
Emission Maximum |
Add to Cart |
| 1 |
OR
|
CNVFP-ADAMTS4-00075-OR |
573nm |
548nm |
|
| 2 |
RE
|
CNVFP-ADAMTS4-00075-RE |
599nm |
580nm |
|
| 3 |
GO
|
CNVFP-ADAMTS4-00075-GO |
551nm |
525nm |
|
| 4 |
GR
|
CNVFP-ADAMTS4-00075-GR |
515nm |
491nm |
|
| 5 |
AQ
|
CNVFP-ADAMTS4-00075-AQ |
467nm |
418nm |
|
Other Products
