Gene-specific Copy Number Variation Probe-ADAM17
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| Catalog: |
CNVFP-ADAM17-00083 |
| Classification: |
Copy Number Variation |
| Description: |
Our Gene-specific Copy Number Variation Probes usually target the flanks of the target gene (ADAM17). The product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We provide CNV FISH Probes with a variety of dye color combinations to meet various challenges. Probe products not only provide some classic color combinations but also provide customized probe services. |
| Application: |
ADAM17 Gene-specific copy number variation probes are mainly used to detect the copy number variation related to ADAM17 genes. This product achieves the purpose of detection by hybridizing with the ADAM17 gene. Due to this design method, our probe products can detect the amplification and deletion of target genes on chromosomes through FISH. |
| Category: |
Copy Number Variation |
| Probe Kits Volume (µL): |
40 μL |
| Quantity: |
20 Tests |
| Hybridization Solution (µL): |
200 μL |
| Turnaround Time: |
7-10 Business Days |
| Shipping Time: |
1-2 Day Expedited Shipping |
| Storage Conditions: |
Store at -20℃ and avoid light; |
| Shipping Conditions: |
-20℃ |
Gene Details
| Gene Name |
ADAM Metallopeptidase Domain 17 |
| Gene Summary [Provided by RefSeq] |
This gene encodes a member of the ADAM (a disintegrin and metalloprotease domain) family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biologic processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. The encoded preproprotein is proteolytically processed to generate the mature protease. The encoded protease functions in the ectodomain shedding of tumor necrosis factor-alpha, in which soluble tumor necrosis factor-alpha is released from the membrane-bound precursor. This protease also functions in the processing of numerous other substrates, including cell adhesion proteins, cytokine and growth factor receptors and epidermal growth factor (EGF) receptor ligands. The encoded protein also plays a prominent role in the activation of the Notch signaling pathway. Elevated expression of this gene has been observed in specific cell types derived from psoriasis, rheumatoid arthritis, multiple sclerosis and Crohn's disease patients, suggesting that the encoded protein may play a role in autoimmune disease. [provided by RefSeq, Feb 2016] |
| Gene Symbol |
ADAM17 |
| Location |
2p25.1 |
| Chromosome |
Chromosome2 |
| Coordinates |
This gene maps to 9629410-9695917 in GRCh37 coordinates. |
| Species |
Human |
Dye Colors:
OR
RE
GO
GR
AQ
Order Sheet
| Number |
Dye Color |
Order Name |
Absorbance Maximum |
Emission Maximum |
Add to Cart |
| 1 |
OR
|
CNVFP-ADAM17-00083-OR |
573nm |
548nm |
|
| 2 |
RE
|
CNVFP-ADAM17-00083-RE |
599nm |
580nm |
|
| 3 |
GO
|
CNVFP-ADAM17-00083-GO |
551nm |
525nm |
|
| 4 |
GR
|
CNVFP-ADAM17-00083-GR |
515nm |
491nm |
|
| 5 |
AQ
|
CNVFP-ADAM17-00083-AQ |
467nm |
418nm |
|
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