Gene-specific Copy Number Variation Probe-ACVR2B
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| Catalog: |
CNVFP-ACVR2B-00095 |
| Classification: |
Copy Number Variation |
| Description: |
Our Gene-specific Copy Number Variation Probes usually target the flanks of the target gene (ACVR2B). The product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We provide CNV FISH Probes with a variety of dye color combinations to meet various challenges. Probe products not only provide some classic color combinations but also provide customized probe services. |
| Application: |
ACVR2B Gene-specific copy number variation probes are mainly used to detect the copy number variation related to ACVR2B genes. This product achieves the purpose of detection by hybridizing with the ACVR2B gene. Due to this design method, our probe products can detect the amplification and deletion of target genes on chromosomes through FISH. |
| Category: |
Copy Number Variation |
| Probe Kits Volume (µL): |
40 μL |
| Quantity: |
20 Tests |
| Hybridization Solution (µL): |
200 μL |
| Turnaround Time: |
7-10 Business Days |
| Shipping Time: |
1-2 Day Expedited Shipping |
| Storage Conditions: |
Store at -20℃ and avoid light; |
| Shipping Conditions: |
-20℃ |
Gene Details
| Gene Name |
Activin A Receptor Type 2B |
| Gene Summary [Provided by RefSeq] |
Activins are dimeric growth and differentiation factors which belong to the transforming growth factor-beta (TGF-beta) superfamily of structurally related signaling proteins. Activins signal through a heteromeric complex of receptor serine kinases which include at least two type I (I and IB) and two type II (II and IIB) receptors. These receptors are all transmembrane proteins, composed of a ligand-binding extracellular domain with cysteine-rich region, a transmembrane domain, and a cytoplasmic domain with predicted serine/threonine specificity. Type I receptors are essential for signaling; and type II receptors are required for binding ligands and for expression of type I receptors. Type I and II receptors form a stable complex after ligand binding, resulting in phosphorylation of type I receptors by type II receptors. Type II receptors are considered to be constitutively active kinases. This gene encodes activin A type IIB receptor, which displays a 3- to 4-fold higher affinity for the ligand than activin A type II receptor. [provided by RefSeq, Jul 2008] |
| Gene Symbol |
ACVR2B |
| Location |
3p22.2 |
| Chromosome |
Chromosome3 |
| Coordinates |
This gene maps to 38495789-38534633 in GRCh37 coordinates. |
| Species |
Human |
Dye Colors:
OR
RE
GO
GR
AQ
Order Sheet
| Number |
Dye Color |
Order Name |
Absorbance Maximum |
Emission Maximum |
Add to Cart |
| 1 |
OR
|
CNVFP-ACVR2B-00095-OR |
573nm |
548nm |
|
| 2 |
RE
|
CNVFP-ACVR2B-00095-RE |
599nm |
580nm |
|
| 3 |
GO
|
CNVFP-ACVR2B-00095-GO |
551nm |
525nm |
|
| 4 |
GR
|
CNVFP-ACVR2B-00095-GR |
515nm |
491nm |
|
| 5 |
AQ
|
CNVFP-ACVR2B-00095-AQ |
467nm |
418nm |
|
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