Gene-specific Copy Number Variation Probe-ACO1
Add to Cart
| Catalog: |
CNVFP-ACO1-00154 |
| Classification: |
Copy Number Variation |
| Description: |
Our Gene-specific Copy Number Variation Probes usually target the flanks of the target gene (ACO1). The product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We provide CNV FISH Probes with a variety of dye color combinations to meet various challenges. Probe products not only provide some classic color combinations but also provide customized probe services. |
| Application: |
ACO1 Gene-specific copy number variation probes are mainly used to detect the copy number variation related to ACO1 genes. This product achieves the purpose of detection by hybridizing with the ACO1 gene. Due to this design method, our probe products can detect the amplification and deletion of target genes on chromosomes through FISH. |
| Category: |
Copy Number Variation |
| Probe Kits Volume (µL): |
40 μL |
| Quantity: |
20 Tests |
| Hybridization Solution (µL): |
200 μL |
| Turnaround Time: |
7-10 Business Days |
| Shipping Time: |
1-2 Day Expedited Shipping |
| Storage Conditions: |
Store at -20℃ and avoid light; |
| Shipping Conditions: |
-20℃ |
Gene Details
| Gene Name |
Aconitase 1 |
| Gene Summary [Provided by RefSeq] |
The protein encoded by this gene is a bifunctional, cytosolic protein that functions as an essential enzyme in the TCA cycle and interacts with mRNA to control the levels of iron inside cells. When cellular iron levels are high, this protein binds to a 4Fe-4S cluster and functions as an aconitase. Aconitases are iron-sulfur proteins that function to catalyze the conversion of citrate to isocitrate. When cellular iron levels are low, the protein binds to iron-responsive elements (IREs), which are stem-loop structures found in the 5' UTR of ferritin mRNA, and in the 3' UTR of transferrin receptor mRNA. When the protein binds to IRE, it results in repression of translation of ferritin mRNA, and inhibition of degradation of the otherwise rapidly degraded transferrin receptor mRNA. The encoded protein has been identified as a moonlighting protein based on its ability to perform mechanistically distinct functions. Alternative splicing results in multiple transcript variants [provided by RefSeq, Jan 2014] |
| Gene Symbol |
ACO1 |
| Location |
9p21.1 |
| Chromosome |
Chromosome9 |
| Coordinates |
This gene maps to 32384600-32450832 in GRCh37 coordinates. |
| Species |
Human |
Dye Colors:
OR
RE
GO
GR
AQ
Order Sheet
| Number |
Dye Color |
Order Name |
Absorbance Maximum |
Emission Maximum |
Add to Cart |
| 1 |
OR
|
CNVFP-ACO1-00154-OR |
573nm |
548nm |
|
| 2 |
RE
|
CNVFP-ACO1-00154-RE |
599nm |
580nm |
|
| 3 |
GO
|
CNVFP-ACO1-00154-GO |
551nm |
525nm |
|
| 4 |
GR
|
CNVFP-ACO1-00154-GR |
515nm |
491nm |
|
| 5 |
AQ
|
CNVFP-ACO1-00154-AQ |
467nm |
418nm |
|
Other Products
