Gene-specific Copy Number Variation Probe-ABL1
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| Catalog: |
CNVFP-ABL1-00237 |
| Classification: |
Copy Number Variation |
| Description: |
Our Gene-specific Copy Number Variation Probes usually target the flanks of the target gene (ABL1). The product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We provide CNV FISH Probes with a variety of dye color combinations to meet various challenges. Probe products not only provide some classic color combinations but also provide customized probe services. |
| Application: |
ABL1 Gene-specific copy number variation probes are mainly used to detect the copy number variation related to ABL1 genes. This product achieves the purpose of detection by hybridizing with the ABL1 gene. Due to this design method, our probe products can detect the amplification and deletion of target genes on chromosomes through FISH. |
| Category: |
Copy Number Variation |
| Probe Kits Volume (µL): |
40 μL |
| Quantity: |
20 Tests |
| Hybridization Solution (µL): |
200 μL |
| Turnaround Time: |
7-10 Business Days |
| Shipping Time: |
1-2 Day Expedited Shipping |
| Storage Conditions: |
Store at -20℃ and avoid light; |
| Shipping Conditions: |
-20℃ |
Gene Details
| Gene Name |
ABL Proto-oncogene 1, Non-receptor Tyrosine Kinase |
| Gene Summary [Provided by RefSeq] |
This gene is a protooncogene that encodes a protein tyrosine kinase involved in a variety of cellular processes, including cell division, adhesion, differentiation, and response to stress. The activity of the protein is negatively regulated by its SH3 domain, whereby deletion of the region encoding this domain results in an oncogene. The ubiquitously expressed protein has DNA-binding activity that is regulated by CDC2-mediated phosphorylation, suggesting a cell cycle function. This gene has been found fused to a variety of translocation partner genes in various leukemias, most notably the t(9;22) translocation that results in a fusion with the 5' end of the breakpoint cluster region gene (BCR; MIM:151410). Alternative splicing of this gene results in two transcript variants, which contain alternative first exons that are spliced to the remaining common exons. [provided by RefSeq, Aug 2014] |
| Gene Symbol |
ABL1 |
| Location |
9q34.12 |
| Chromosome |
Chromosome9 |
| Coordinates |
This gene maps to 133589267-133763062 in GRCh37 coordinates. |
| Species |
Human |
Dye Colors:
OR
RE
GO
GR
AQ
Order Sheet
| Number |
Dye Color |
Order Name |
Absorbance Maximum |
Emission Maximum |
Add to Cart |
| 1 |
OR
|
CNVFP-ABL1-00237-OR |
573nm |
548nm |
|
| 2 |
RE
|
CNVFP-ABL1-00237-RE |
599nm |
580nm |
|
| 3 |
GO
|
CNVFP-ABL1-00237-GO |
551nm |
525nm |
|
| 4 |
GR
|
CNVFP-ABL1-00237-GR |
515nm |
491nm |
|
| 5 |
AQ
|
CNVFP-ABL1-00237-AQ |
467nm |
418nm |
|
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