Gene-specific Copy Number Variation Probe-ABCD2
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| Catalog: |
CNVFP-ABCD2-00274 |
| Classification: |
Copy Number Variation |
| Description: |
Our Gene-specific Copy Number Variation Probes usually target the flanks of the target gene (ABCD2). The product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We provide CNV FISH Probes with a variety of dye color combinations to meet various challenges. Probe products not only provide some classic color combinations but also provide customized probe services. |
| Application: |
ABCD2 Gene-specific copy number variation probes are mainly used to detect the copy number variation related to ABCD2 genes. This product achieves the purpose of detection by hybridizing with the ABCD2 gene. Due to this design method, our probe products can detect the amplification and deletion of target genes on chromosomes through FISH. |
| Category: |
Copy Number Variation |
| Probe Kits Volume (µL): |
40 μL |
| Quantity: |
20 Tests |
| Hybridization Solution (µL): |
200 μL |
| Turnaround Time: |
7-10 Business Days |
| Shipping Time: |
1-2 Day Expedited Shipping |
| Storage Conditions: |
Store at -20℃ and avoid light; |
| Shipping Conditions: |
-20℃ |
Gene Details
| Gene Name |
ATP Binding Cassette Subfamily D Member 2 |
| Gene Summary [Provided by RefSeq] |
The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the ALD subfamily, which is involved in peroxisomal import of fatty acids and/or fatty acyl-CoAs in the organelle. All known peroxisomal ABC transporters are half transporters which require a partner half transporter molecule to form a functional homodimeric or heterodimeric transporter. The function of this peroxisomal membrane protein is unknown; however this protein is speculated to function as a dimerization partner of ABCD1 and/or other peroxisomal ABC transporters. Mutations in this gene have been observed in patients with adrenoleukodystrophy, a severe demyelinating disease. This gene has been identified as a candidate for a modifier gene, accounting for the extreme variation among adrenoleukodystrophy phenotypes. This gene is also a candidate for a complement group of Zellweger syndrome, a genetically heterogeneous disorder of peroxisomal biogenesis. [provided by RefSeq, Jul 2008] |
| Gene Symbol |
ABCD2 |
| Location |
12q12 |
| Chromosome |
Chromosome12 |
| Coordinates |
This gene maps to 39945021-40013843 in GRCh37 coordinates. |
| Species |
Human |
Dye Colors:
OR
RE
GO
GR
AQ
Order Sheet
| Number |
Dye Color |
Order Name |
Absorbance Maximum |
Emission Maximum |
Add to Cart |
| 1 |
OR
|
CNVFP-ABCD2-00274-OR |
573nm |
548nm |
|
| 2 |
RE
|
CNVFP-ABCD2-00274-RE |
599nm |
580nm |
|
| 3 |
GO
|
CNVFP-ABCD2-00274-GO |
551nm |
525nm |
|
| 4 |
GR
|
CNVFP-ABCD2-00274-GR |
515nm |
491nm |
|
| 5 |
AQ
|
CNVFP-ABCD2-00274-AQ |
467nm |
418nm |
|
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