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| Catalog: | GBAFP-VKORC1-09016 |
| Classification: | Gene-specific Break Apart Probes |
| Description: | Our Gene-specific Break Apart Probes usually target the flanks of the target gene (VKORC1). Due to this design method, our probe products can detect chromosomal rearrangements, such as translocations, by FISH.The product usually consists of a reagent combination composed of a probe with a selected dye color and a hybridization reagent. |
| Application: | VKORC1 Gene-specific Break Apart Probe is designed to detect potential VKORC1 rearrangements. This probe has been confirmed on the metaphase and interphase chromosomes by FISH. We provide a variety of dye color combinations for Break Apart Probes for customers to choose from. Probe products not only provide some classic color combinations, but also provide customized probe services. |
| Quantity: | 20 Tests |
| Probe Kits Volume (µL): | 40 μL |
| Hybridization Solution (µL): | 200 μL |
| Turnaround Time: | Within 10 Business Days |
| Shipping Time: | 1-2 Day Expedited Shipping |
| Shipping Conditions: | -20℃ |
| Storage Conditions: | Store at -20℃ and avoid light; |
| Gene Name | Vitamin K Epoxide Reductase Complex Subunit 1 |
| Gene Summary [Provided by RefSeq] | This gene encodes the catalytic subunit of the vitamin K epoxide reductase complex, which is responsible for the reduction of inactive vitamin K 2,3-epoxide to active vitamin K in the endoplasmic reticulum membrane. Vitamin K is a required co-factor for carboxylation of glutamic acid residues by vitamin K-dependent gamma-carboxylase in blood-clotting enzymes. Allelic variation in this gene is associated with vitamin k-dependent clotting factors combined deficiency of 2, and increased resistance or sensitivity to warfarin, an inhibitor of vitamin K epoxide reductase. Pseudogenes of this gene are located on chromosomes 1 and X. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2015] |
| Gene Symbol | VKORC1 |
| Location | 16p11.2 |
| Chromosome | Chromosome16 |
| Coordinates | This gene maps to 31102174-31106276 in GRCh37 coordinates. |
| Species | Human |
| Number | Dye Color | Order Name | Absorbance Maximum | Emission Maximum | Add to Cart |
| 1 | GR; OR | GBAFP-VKORC1-09016-GROR | 515nm;573nm | 491nm;548nm | |
| 2 | AQ; OR | GBAFP-VKORC1-09016-AQOR | 467nm;573nm | 418nm;548nm | |
| 3 | GO; GR | GBAFP-VKORC1-09016-GOGR | 551nm;515nm | 525nm;491nm | |
| 4 | GO; RE | GBAFP-VKORC1-09016-GORE | 551nm;599nm | 525nm;580nm | |
| 5 | GR; GO | GBAFP-VKORC1-09016-GRGO | 515nm;551nm | 491nm;525nm | |
| 6 | GR; RE | GBAFP-VKORC1-09016-GRRE | 515nm;599nm | 491nm;580nm | |
| 7 | OR; GR | GBAFP-VKORC1-09016-ORGR | 573nm;515nm | 548nm;491nm | |
| 8 | RE; GO | GBAFP-VKORC1-09016-REGO | 599nm;551nm | 580nm;525nm | |
| 9 | RE; GR | GBAFP-VKORC1-09016-REGR | 599nm;515nm | 580nm;491nm |
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