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Gene-specific Break Apart Probe-VKORC1

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Catalog: GBAFP-VKORC1-09016
Classification: Gene-specific Break Apart Probes
Description: Our Gene-specific Break Apart Probes usually target the flanks of the target gene (VKORC1). Due to this design method, our probe products can detect chromosomal rearrangements, such as translocations, by FISH.The product usually consists of a reagent combination composed of a probe with a selected dye color and a hybridization reagent.
Application: VKORC1 Gene-specific Break Apart Probe is designed to detect potential VKORC1 rearrangements. This probe has been confirmed on the metaphase and interphase chromosomes by FISH. We provide a variety of dye color combinations for Break Apart Probes for customers to choose from. Probe products not only provide some classic color combinations, but also provide customized probe services.
Quantity: 20 Tests
Probe Kits Volume (µL): 40 μL
Hybridization Solution (µL): 200 μL
Turnaround Time: Within 10 Business Days
Shipping Time: 1-2 Day Expedited Shipping
Shipping Conditions: -20℃
Storage Conditions: Store at -20℃ and avoid light;

Gene Details

Gene Name Vitamin K Epoxide Reductase Complex Subunit 1
Gene Summary [Provided by RefSeq] This gene encodes the catalytic subunit of the vitamin K epoxide reductase complex, which is responsible for the reduction of inactive vitamin K 2,3-epoxide to active vitamin K in the endoplasmic reticulum membrane. Vitamin K is a required co-factor for carboxylation of glutamic acid residues by vitamin K-dependent gamma-carboxylase in blood-clotting enzymes. Allelic variation in this gene is associated with vitamin k-dependent clotting factors combined deficiency of 2, and increased resistance or sensitivity to warfarin, an inhibitor of vitamin K epoxide reductase. Pseudogenes of this gene are located on chromosomes 1 and X. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2015]
Gene Symbol VKORC1
Location 16p11.2
Chromosome Chromosome16
Coordinates This gene maps to 31102174-31106276 in GRCh37 coordinates.
Species Human

Order Sheet

Number Dye Color Order Name Absorbance Maximum Emission Maximum Add to Cart
1 GR; OR GBAFP-VKORC1-09016-GROR 515nm;573nm 491nm;548nm
2 AQ; OR GBAFP-VKORC1-09016-AQOR 467nm;573nm 418nm;548nm
3 GO; GR GBAFP-VKORC1-09016-GOGR 551nm;515nm 525nm;491nm
4 GO; RE GBAFP-VKORC1-09016-GORE 551nm;599nm 525nm;580nm
5 GR; GO GBAFP-VKORC1-09016-GRGO 515nm;551nm 491nm;525nm
6 GR; RE GBAFP-VKORC1-09016-GRRE 515nm;599nm 491nm;580nm
7 OR; GR GBAFP-VKORC1-09016-ORGR 573nm;515nm 548nm;491nm
8 RE; GO GBAFP-VKORC1-09016-REGO 599nm;551nm 580nm;525nm
9 RE; GR GBAFP-VKORC1-09016-REGR 599nm;515nm 580nm;491nm

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