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| Catalog: | GBAFP-VCL-18799 |
| Classification: | Gene-specific Break Apart Probes |
| Description: | Our Gene-specific Break Apart Probes usually target the flanks of the target gene (VCL). Due to this design method, our probe products can detect chromosomal rearrangements, such as translocations, by FISH.The product usually consists of a reagent combination composed of a probe with a selected dye color and a hybridization reagent. |
| Application: | VCL Gene-specific Break Apart Probe is designed to detect potential VCL rearrangements. This probe has been confirmed on the metaphase and interphase chromosomes by FISH. We provide a variety of dye color combinations for Break Apart Probes for customers to choose from. Probe products not only provide some classic color combinations, but also provide customized probe services. |
| Quantity: | 20 Tests |
| Probe Kits Volume (µL): | 40 μL |
| Hybridization Solution (µL): | 200 μL |
| Turnaround Time: | Within 10 Business Days |
| Shipping Time: | 1-2 Day Expedited Shipping |
| Shipping Conditions: | -20℃ |
| Storage Conditions: | Store at -20℃ and avoid light; |
| Gene Name | Vinculin |
| Gene Summary [Provided by RefSeq] | Vinculin is a cytoskeletal protein associated with cell-cell and cell-matrix junctions, where it is thought to function as one of several interacting proteins involved in anchoring F-actin to the membrane. Defects in VCL are the cause of cardiomyopathy dilated type 1W. Dilated cardiomyopathy is a disorder characterized by ventricular dilation and impaired systolic function, resulting in congestive heart failure and arrhythmia. Multiple alternatively spliced transcript variants have been found for this gene, but the biological validity of some variants has not been determined. [provided by RefSeq, Jul 2008] |
| Gene Symbol | VCL |
| Location | 10q22.2 |
| Chromosome | Chromosome10 |
| Coordinates | This gene maps to 75757871-75879914 in GRCh37 coordinates. |
| Species | Human |
| Number | Dye Color | Order Name | Absorbance Maximum | Emission Maximum | Add to Cart |
| 1 | OR; GR | GBAFP-VCL-18799-ORGR | 573nm;515nm | 548nm;491nm | |
| 2 | AQ; OR | GBAFP-VCL-18799-AQOR | 467nm;573nm | 418nm;548nm | |
| 3 | GO; GR | GBAFP-VCL-18799-GOGR | 551nm;515nm | 525nm;491nm | |
| 4 | GO; RE | GBAFP-VCL-18799-GORE | 551nm;599nm | 525nm;580nm | |
| 5 | GR; GO | GBAFP-VCL-18799-GRGO | 515nm;551nm | 491nm;525nm | |
| 6 | GR; OR | GBAFP-VCL-18799-GROR | 515nm;573nm | 491nm;548nm | |
| 7 | GR; RE | GBAFP-VCL-18799-GRRE | 515nm;599nm | 491nm;580nm | |
| 8 | RE; GO | GBAFP-VCL-18799-REGO | 599nm;551nm | 580nm;525nm | |
| 9 | RE; GR | GBAFP-VCL-18799-REGR | 599nm;515nm | 580nm;491nm |
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