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| Catalog: | GBAFP-UNC13B-18610 |
| Classification: | Gene-specific Break Apart Probes |
| Description: | Our Gene-specific Break Apart Probes usually target the flanks of the target gene (UNC13B). Due to this design method, our probe products can detect chromosomal rearrangements, such as translocations, by FISH.The product usually consists of a reagent combination composed of a probe with a selected dye color and a hybridization reagent. |
| Application: | UNC13B Gene-specific Break Apart Probe is designed to detect potential UNC13B rearrangements. This probe has been confirmed on the metaphase and interphase chromosomes by FISH. We provide a variety of dye color combinations for Break Apart Probes for customers to choose from. Probe products not only provide some classic color combinations, but also provide customized probe services. |
| Quantity: | 20 Tests |
| Probe Kits Volume (µL): | 40 μL |
| Hybridization Solution (µL): | 200 μL |
| Turnaround Time: | Within 10 Business Days |
| Shipping Time: | 1-2 Day Expedited Shipping |
| Shipping Conditions: | -20℃ |
| Storage Conditions: | Store at -20℃ and avoid light; |
| Gene Name | Unc-13 Homolog B |
| Gene Summary [Provided by RefSeq] | This gene is expressed in the kidney cortical epithelial cells and is upregulated by hyperglycemia. The encoded protein shares a high level of similarity to the rat homolog, and contains 3 C2 domains and a diacylglycerol-binding C1 domain. Hyperglycemia increases the levels of diacylglycerol, which has been shown to induce apoptosis in cells transfected with this gene and thus contribute to the renal cell complications of hyperglycemia. Studies in other species also indicate a role for this protein in the priming step of synaptic vesicle exocytosis. [provided by RefSeq, Jul 2008] |
| Gene Symbol | UNC13B |
| Location | 9p13.3 |
| Chromosome | Chromosome9 |
| Coordinates | This gene maps to 35161988-35405332 in GRCh37 coordinates. |
| Species | Human |
| Number | Dye Color | Order Name | Absorbance Maximum | Emission Maximum | Add to Cart |
| 1 | OR; GR | GBAFP-UNC13B-18610-ORGR | 573nm;515nm | 548nm;491nm | |
| 2 | AQ; OR | GBAFP-UNC13B-18610-AQOR | 467nm;573nm | 418nm;548nm | |
| 3 | GO; GR | GBAFP-UNC13B-18610-GOGR | 551nm;515nm | 525nm;491nm | |
| 4 | GO; RE | GBAFP-UNC13B-18610-GORE | 551nm;599nm | 525nm;580nm | |
| 5 | GR; GO | GBAFP-UNC13B-18610-GRGO | 515nm;551nm | 491nm;525nm | |
| 6 | GR; OR | GBAFP-UNC13B-18610-GROR | 515nm;573nm | 491nm;548nm | |
| 7 | GR; RE | GBAFP-UNC13B-18610-GRRE | 515nm;599nm | 491nm;580nm | |
| 8 | RE; GO | GBAFP-UNC13B-18610-REGO | 599nm;551nm | 580nm;525nm | |
| 9 | RE; GR | GBAFP-UNC13B-18610-REGR | 599nm;515nm | 580nm;491nm |
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