Gene-specific Break Apart Probe-TRAF6

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Catalog:	GBAFP-TRAF6-08574
Classification:	Gene-specific Break Apart Probes
Description:	Our Gene-specific Break Apart Probes usually target the flanks of the target gene (TRAF6). Due to this design method, our probe products can detect chromosomal rearrangements, such as translocations, by FISH.The product usually consists of a reagent combination composed of a probe with a selected dye color and a hybridization reagent.
Application:	TRAF6 Gene-specific Break Apart Probe is designed to detect potential TRAF6 rearrangements. This probe has been confirmed on the metaphase and interphase chromosomes by FISH. We provide a variety of dye color combinations for Break Apart Probes for customers to choose from. Probe products not only provide some classic color combinations, but also provide customized probe services.
Quantity:	20 Tests
Probe Kits Volume (µL):	40 μL
Hybridization Solution (µL):	200 μL
Turnaround Time:	Within 10 Business Days
Shipping Time:	1-2 Day Expedited Shipping
Shipping Conditions:	-20℃
Storage Conditions:	Store at -20℃ and avoid light;

Gene Details

Gene Name	TNF Receptor Associated Factor 6
Gene Summary [Provided by RefSeq]	The protein encoded by this gene is a member of the TNF receptor associated factor (TRAF) protein family. TRAF proteins are associated with, and mediate signal transduction from, members of the TNF receptor superfamily. This protein mediates signaling from members of the TNF receptor superfamily as well as the Toll/IL-1 family. Signals from receptors such as CD40, TNFSF11/RANCE and IL-1 have been shown to be mediated by this protein. This protein also interacts with various protein kinases including IRAK1/IRAK, SRC and PKCzeta, which provides a link between distinct signaling pathways. This protein functions as a signal transducer in the NF-kappaB pathway that activates IkappaB kinase (IKK) in response to proinflammatory cytokines. The interaction of this protein with UBE2N/UBC13, and UBE2V1/UEV1A, which are ubiquitin conjugating enzymes catalyzing the formation of polyubiquitin chains, has been found to be required for IKK activation by this protein. This protein also interacts with the transforming growth factor (TGF) beta receptor complex and is required for Smad-independent activation of the JNK and p38 kinases. This protein has an amino terminal RING domain which is followed by four zinc-finger motifs, a central coiled-coil region and a highly conserved carboxyl terminal domain, known as the TRAF-C domain. Two alternatively spliced transcript variants, encoding an identical protein, have been reported. [provided by RefSeq, Feb 2012]
Gene Symbol	TRAF6
Location	11p12
Chromosome	Chromosome11
Coordinates	This gene maps to 36505316-36531863 in GRCh37 coordinates.
Species	Human

Order Sheet

Number	Dye Color	Order Name	Absorbance Maximum	Emission Maximum	Add to Cart
1	GR; OR	GBAFP-TRAF6-08574-GROR	515nm;573nm	491nm;548nm
2	AQ; OR	GBAFP-TRAF6-08574-AQOR	467nm;573nm	418nm;548nm
3	GO; GR	GBAFP-TRAF6-08574-GOGR	551nm;515nm	525nm;491nm
4	GO; RE	GBAFP-TRAF6-08574-GORE	551nm;599nm	525nm;580nm
5	GR; GO	GBAFP-TRAF6-08574-GRGO	515nm;551nm	491nm;525nm
6	GR; RE	GBAFP-TRAF6-08574-GRRE	515nm;599nm	491nm;580nm
7	OR; GR	GBAFP-TRAF6-08574-ORGR	573nm;515nm	548nm;491nm
8	RE; GO	GBAFP-TRAF6-08574-REGO	599nm;551nm	580nm;525nm
9	RE; GR	GBAFP-TRAF6-08574-REGR	599nm;515nm	580nm;491nm

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