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| Catalog: | GBAFP-TOP3A-08614 |
| Classification: | Gene-specific Break Apart Probes |
| Description: | Our Gene-specific Break Apart Probes usually target the flanks of the target gene (TOP3A). Due to this design method, our probe products can detect chromosomal rearrangements, such as translocations, by FISH.The product usually consists of a reagent combination composed of a probe with a selected dye color and a hybridization reagent. |
| Application: | TOP3A Gene-specific Break Apart Probe is designed to detect potential TOP3A rearrangements. This probe has been confirmed on the metaphase and interphase chromosomes by FISH. We provide a variety of dye color combinations for Break Apart Probes for customers to choose from. Probe products not only provide some classic color combinations, but also provide customized probe services. |
| Quantity: | 20 Tests |
| Probe Kits Volume (µL): | 40 μL |
| Hybridization Solution (µL): | 200 μL |
| Turnaround Time: | Within 10 Business Days |
| Shipping Time: | 1-2 Day Expedited Shipping |
| Shipping Conditions: | -20℃ |
| Storage Conditions: | Store at -20℃ and avoid light; |
| Gene Name | DNA Topoisomerase III Alpha |
| Gene Summary [Provided by RefSeq] | This gene encodes a DNA topoisomerase, an enzyme that controls and alters the topologic states of DNA during transcription. This enzyme catalyzes the transient breaking and rejoining of a single strand of DNA which allows the strands to pass through one another, thus reducing the number of supercoils and altering the topology of DNA. This enzyme forms a complex with BLM which functions in the regulation of recombination in somatic cells. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Mar 2016] |
| Gene Symbol | TOP3A |
| Location | 17p11.2 |
| Chromosome | Chromosome17 |
| Coordinates | This gene maps to 18177234-18218321 in GRCh37 coordinates. |
| Species | Human |
| Number | Dye Color | Order Name | Absorbance Maximum | Emission Maximum | Add to Cart |
| 1 | GR; OR | GBAFP-TOP3A-08614-GROR | 515nm;573nm | 491nm;548nm | |
| 2 | AQ; OR | GBAFP-TOP3A-08614-AQOR | 467nm;573nm | 418nm;548nm | |
| 3 | GO; GR | GBAFP-TOP3A-08614-GOGR | 551nm;515nm | 525nm;491nm | |
| 4 | GO; RE | GBAFP-TOP3A-08614-GORE | 551nm;599nm | 525nm;580nm | |
| 5 | GR; GO | GBAFP-TOP3A-08614-GRGO | 515nm;551nm | 491nm;525nm | |
| 6 | GR; RE | GBAFP-TOP3A-08614-GRRE | 515nm;599nm | 491nm;580nm | |
| 7 | OR; GR | GBAFP-TOP3A-08614-ORGR | 573nm;515nm | 548nm;491nm | |
| 8 | RE; GO | GBAFP-TOP3A-08614-REGO | 599nm;551nm | 580nm;525nm | |
| 9 | RE; GR | GBAFP-TOP3A-08614-REGR | 599nm;515nm | 580nm;491nm |
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