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| Catalog: | GBAFP-TOP1MT-08618 |
| Classification: | Gene-specific Break Apart Probes |
| Description: | Our Gene-specific Break Apart Probes usually target the flanks of the target gene (TOP1MT). Due to this design method, our probe products can detect chromosomal rearrangements, such as translocations, by FISH.The product usually consists of a reagent combination composed of a probe with a selected dye color and a hybridization reagent. |
| Application: | TOP1MT Gene-specific Break Apart Probe is designed to detect potential TOP1MT rearrangements. This probe has been confirmed on the metaphase and interphase chromosomes by FISH. We provide a variety of dye color combinations for Break Apart Probes for customers to choose from. Probe products not only provide some classic color combinations, but also provide customized probe services. |
| Quantity: | 20 Tests |
| Probe Kits Volume (µL): | 40 μL |
| Hybridization Solution (µL): | 200 μL |
| Turnaround Time: | Within 10 Business Days |
| Shipping Time: | 1-2 Day Expedited Shipping |
| Shipping Conditions: | -20℃ |
| Storage Conditions: | Store at -20℃ and avoid light; |
| Gene Name | DNA Topoisomerase I Mitochondrial |
| Gene Summary [Provided by RefSeq] | This gene encodes a mitochondrial DNA topoisomerase that plays a role in the modification of DNA topology. The encoded protein is a type IB topoisomerase and catalyzes the transient breaking and rejoining of DNA to relieve tension and DNA supercoiling generated in the mitochondrial genome during replication and transcription. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, May 2012] |
| Gene Symbol | TOP1MT |
| Location | 8q24.3 |
| Chromosome | Chromosome8 |
| Coordinates | This gene maps to 144391527-144417050 in GRCh37 coordinates. |
| Species | Human |
| Number | Dye Color | Order Name | Absorbance Maximum | Emission Maximum | Add to Cart |
| 1 | GR; OR | GBAFP-TOP1MT-08618-GROR | 515nm;573nm | 491nm;548nm | |
| 2 | AQ; OR | GBAFP-TOP1MT-08618-AQOR | 467nm;573nm | 418nm;548nm | |
| 3 | GO; GR | GBAFP-TOP1MT-08618-GOGR | 551nm;515nm | 525nm;491nm | |
| 4 | GO; RE | GBAFP-TOP1MT-08618-GORE | 551nm;599nm | 525nm;580nm | |
| 5 | GR; GO | GBAFP-TOP1MT-08618-GRGO | 515nm;551nm | 491nm;525nm | |
| 6 | GR; RE | GBAFP-TOP1MT-08618-GRRE | 515nm;599nm | 491nm;580nm | |
| 7 | OR; GR | GBAFP-TOP1MT-08618-ORGR | 573nm;515nm | 548nm;491nm | |
| 8 | RE; GO | GBAFP-TOP1MT-08618-REGO | 599nm;551nm | 580nm;525nm | |
| 9 | RE; GR | GBAFP-TOP1MT-08618-REGR | 599nm;515nm | 580nm;491nm |
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