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| Catalog: | GBAFP-TMEM2-08449 |
| Classification: | Gene-specific Break Apart Probes |
| Description: | Our Gene-specific Break Apart Probes usually target the flanks of the target gene (TMEM2). Due to this design method, our probe products can detect chromosomal rearrangements, such as translocations, by FISH.The product usually consists of a reagent combination composed of a probe with a selected dye color and a hybridization reagent. |
| Application: | TMEM2 Gene-specific Break Apart Probe is designed to detect potential TMEM2 rearrangements. This probe has been confirmed on the metaphase and interphase chromosomes by FISH. We provide a variety of dye color combinations for Break Apart Probes for customers to choose from. Probe products not only provide some classic color combinations, but also provide customized probe services. |
| Quantity: | 20 Tests |
| Probe Kits Volume (µL): | 40 μL |
| Hybridization Solution (µL): | 200 μL |
| Turnaround Time: | Within 10 Business Days |
| Shipping Time: | 1-2 Day Expedited Shipping |
| Shipping Conditions: | -20℃ |
| Storage Conditions: | Store at -20℃ and avoid light; |
| Gene Name | Transmembrane Protein 2 |
| Gene Summary [Provided by RefSeq] | This gene encodes a type II transmembrane protein that belongs to the interferon-induced transmembrane (IFITM) protein superfamily. The encoded protein functions as a cell surface hyaluronidase that cleaves extracellular high molecular weight hyaluronan into intermediate size fragments before internalization and degradation in the lysosome. It also has an interferon-mediated antiviral function in humans through activation of the JAK STAT signaling pathway. The activation of this gene by transcription factor SOX4 in breast cancer cells has been shown to mediate the pathological effects of SOX4 on cancer progression. Naturally occurring mutations in this gene are associated with autosomal recessive non-syndromic hearing loss. [provided by RefSeq, Mar 2017] |
| Gene Symbol | TMEM2 |
| Location | 9q21.13 |
| Chromosome | Chromosome9 |
| Coordinates | This gene maps to 74298281-74383800 in GRCh37 coordinates. |
| Species | Human |
| Number | Dye Color | Order Name | Absorbance Maximum | Emission Maximum | Add to Cart |
| 1 | GR; OR | GBAFP-TMEM2-08449-GROR | 515nm;573nm | 491nm;548nm | |
| 2 | AQ; OR | GBAFP-TMEM2-08449-AQOR | 467nm;573nm | 418nm;548nm | |
| 3 | GO; GR | GBAFP-TMEM2-08449-GOGR | 551nm;515nm | 525nm;491nm | |
| 4 | GO; RE | GBAFP-TMEM2-08449-GORE | 551nm;599nm | 525nm;580nm | |
| 5 | GR; GO | GBAFP-TMEM2-08449-GRGO | 515nm;551nm | 491nm;525nm | |
| 6 | GR; RE | GBAFP-TMEM2-08449-GRRE | 515nm;599nm | 491nm;580nm | |
| 7 | OR; GR | GBAFP-TMEM2-08449-ORGR | 573nm;515nm | 548nm;491nm | |
| 8 | RE; GO | GBAFP-TMEM2-08449-REGO | 599nm;551nm | 580nm;525nm | |
| 9 | RE; GR | GBAFP-TMEM2-08449-REGR | 599nm;515nm | 580nm;491nm |
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