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| Catalog: | GBAFP-TMC8-18099 |
| Classification: | Gene-specific Break Apart Probes |
| Description: | Our Gene-specific Break Apart Probes usually target the flanks of the target gene (TMC8). Due to this design method, our probe products can detect chromosomal rearrangements, such as translocations, by FISH.The product usually consists of a reagent combination composed of a probe with a selected dye color and a hybridization reagent. |
| Application: | TMC8 Gene-specific Break Apart Probe is designed to detect potential TMC8 rearrangements. This probe has been confirmed on the metaphase and interphase chromosomes by FISH. We provide a variety of dye color combinations for Break Apart Probes for customers to choose from. Probe products not only provide some classic color combinations, but also provide customized probe services. |
| Quantity: | 20 Tests |
| Probe Kits Volume (µL): | 40 μL |
| Hybridization Solution (µL): | 200 μL |
| Turnaround Time: | Within 10 Business Days |
| Shipping Time: | 1-2 Day Expedited Shipping |
| Shipping Conditions: | -20℃ |
| Storage Conditions: | Store at -20℃ and avoid light; |
| Gene Name | Transmembrane Channel Like 8 |
| Gene Summary [Provided by RefSeq] | Epidermodysplasia verruciformis (EV) is an autosomal recessive dermatosis characterized by abnormal susceptibility to human papillomaviruses (HPVs) and a high rate of progression to squamous cell carcinoma on sun-exposed skin. EV is caused by mutations in either of two adjacent genes located on chromosome 17q25.3. Both of these genes encode integral membrane proteins that localize to the endoplasmic reticulum and are predicted to form transmembrane channels. This gene encodes a transmembrane channel-like protein with 8 predicted transmembrane domains and 3 leucine zipper motifs. [provided by RefSeq, Jul 2008] |
| Gene Symbol | TMC8 |
| Location | 17q25.3 |
| Chromosome | Chromosome17 |
| Coordinates | This gene maps to 76126858-76139049 in GRCh37 coordinates. |
| Species | Human |
| Number | Dye Color | Order Name | Absorbance Maximum | Emission Maximum | Add to Cart |
| 1 | OR; GR | GBAFP-TMC8-18099-ORGR | 573nm;515nm | 548nm;491nm | |
| 2 | AQ; OR | GBAFP-TMC8-18099-AQOR | 467nm;573nm | 418nm;548nm | |
| 3 | GO; GR | GBAFP-TMC8-18099-GOGR | 551nm;515nm | 525nm;491nm | |
| 4 | GO; RE | GBAFP-TMC8-18099-GORE | 551nm;599nm | 525nm;580nm | |
| 5 | GR; GO | GBAFP-TMC8-18099-GRGO | 515nm;551nm | 491nm;525nm | |
| 6 | GR; OR | GBAFP-TMC8-18099-GROR | 515nm;573nm | 491nm;548nm | |
| 7 | GR; RE | GBAFP-TMC8-18099-GRRE | 515nm;599nm | 491nm;580nm | |
| 8 | RE; GO | GBAFP-TMC8-18099-REGO | 599nm;551nm | 580nm;525nm | |
| 9 | RE; GR | GBAFP-TMC8-18099-REGR | 599nm;515nm | 580nm;491nm |
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