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| Catalog: | GBAFP-TCF4-08237 |
| Classification: | Gene-specific Break Apart Probes |
| Description: | Our Gene-specific Break Apart Probes usually target the flanks of the target gene (TCF4). Due to this design method, our probe products can detect chromosomal rearrangements, such as translocations, by FISH.The product usually consists of a reagent combination composed of a probe with a selected dye color and a hybridization reagent. |
| Application: | TCF4 Gene-specific Break Apart Probe is designed to detect potential TCF4 rearrangements. This probe has been confirmed on the metaphase and interphase chromosomes by FISH. We provide a variety of dye color combinations for Break Apart Probes for customers to choose from. Probe products not only provide some classic color combinations, but also provide customized probe services. |
| Quantity: | 20 Tests |
| Probe Kits Volume (µL): | 40 μL |
| Hybridization Solution (µL): | 200 μL |
| Turnaround Time: | Within 10 Business Days |
| Shipping Time: | 1-2 Day Expedited Shipping |
| Shipping Conditions: | -20℃ |
| Storage Conditions: | Store at -20℃ and avoid light; |
| Gene Name | Transcription Factor 4 |
| Gene Summary [Provided by RefSeq] | This gene encodes transcription factor 4, a basic helix-loop-helix transcription factor. The encoded protein recognizes an Ephrussi-box ('E-box') binding site ('CANNTG') - a motif first identified in immunoglobulin enhancers. This gene is broadly expressed, and may play an important role in nervous system development. Defects in this gene are a cause of Pitt-Hopkins syndrome. In addition, an intronic CTG repeat normally numbering 10-37 repeat units can expand to >50 repeat units and cause Fuchs endothelial corneal dystrophy. Multiple alternatively spliced transcript variants that encode different proteins have been described. [provided by RefSeq, Jul 2016] |
| Gene Symbol | TCF4 |
| Location | 18q21.2 |
| Chromosome | Chromosome18 |
| Coordinates | This gene maps to 52889561-53303188 in GRCh37 coordinates. |
| Species | Human |
| Number | Dye Color | Order Name | Absorbance Maximum | Emission Maximum | Add to Cart |
| 1 | GR; OR | GBAFP-TCF4-08237-GROR | 515nm;573nm | 491nm;548nm | |
| 2 | AQ; OR | GBAFP-TCF4-08237-AQOR | 467nm;573nm | 418nm;548nm | |
| 3 | GO; GR | GBAFP-TCF4-08237-GOGR | 551nm;515nm | 525nm;491nm | |
| 4 | GO; RE | GBAFP-TCF4-08237-GORE | 551nm;599nm | 525nm;580nm | |
| 5 | GR; GO | GBAFP-TCF4-08237-GRGO | 515nm;551nm | 491nm;525nm | |
| 6 | GR; RE | GBAFP-TCF4-08237-GRRE | 515nm;599nm | 491nm;580nm | |
| 7 | OR; GR | GBAFP-TCF4-08237-ORGR | 573nm;515nm | 548nm;491nm | |
| 8 | RE; GO | GBAFP-TCF4-08237-REGO | 599nm;551nm | 580nm;525nm | |
| 9 | RE; GR | GBAFP-TCF4-08237-REGR | 599nm;515nm | 580nm;491nm |
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