Gene-specific Break Apart Probe-TAF4

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Catalog:	GBAFP-TAF4-08188
Classification:	Gene-specific Break Apart Probes
Description:	Our Gene-specific Break Apart Probes usually target the flanks of the target gene (TAF4). Due to this design method, our probe products can detect chromosomal rearrangements, such as translocations, by FISH.The product usually consists of a reagent combination composed of a probe with a selected dye color and a hybridization reagent.
Application:	TAF4 Gene-specific Break Apart Probe is designed to detect potential TAF4 rearrangements. This probe has been confirmed on the metaphase and interphase chromosomes by FISH. We provide a variety of dye color combinations for Break Apart Probes for customers to choose from. Probe products not only provide some classic color combinations, but also provide customized probe services.
Quantity:	20 Tests
Probe Kits Volume (µL):	40 μL
Hybridization Solution (µL):	200 μL
Turnaround Time:	Within 10 Business Days
Shipping Time:	1-2 Day Expedited Shipping
Shipping Conditions:	-20℃
Storage Conditions:	Store at -20℃ and avoid light;

Gene Details

Gene Name	TATA-box Binding Protein Associated Factor 4
Gene Summary [Provided by RefSeq]	Initiation of transcription by RNA polymerase II requires the activities of more than 70 polypeptides. The protein that coordinates these activities is transcription factor IID (TFIID), which binds to the core promoter to position the polymerase properly, serves as the scaffold for assembly of the remainder of the transcription complex, and acts as a channel for regulatory signals. TFIID is composed of the TATA-binding protein (TBP) and a group of evolutionarily conserved proteins known as TBP-associated factors or TAFs. TAFs may participate in basal transcription, serve as coactivators, function in promoter recognition or modify general transcription factors (GTFs) to facilitate complex assembly and transcription initiation. This gene encodes one of the larger subunits of TFIID that has been shown to potentiate transcriptional activation by retinoic acid, thyroid hormone and vitamin D3 receptors. In addition, this subunit interacts with the transcription factor CREB, which has a glutamine-rich activation domain, and binds to other proteins containing glutamine-rich regions. Aberrant binding to this subunit by proteins with expanded polyglutamine regions has been suggested as one of the pathogenetic mechanisms underlying a group of neurodegenerative disorders referred to as polyglutamine diseases. [provided by RefSeq, Jul 2008]
Gene Symbol	TAF4
Location	20q13.33
Chromosome	Chromosome20
Coordinates	This gene maps to 60549853-60640866 in GRCh37 coordinates.
Species	Human

Order Sheet

Number	Dye Color	Order Name	Absorbance Maximum	Emission Maximum	Add to Cart
1	GR; OR	GBAFP-TAF4-08188-GROR	515nm;573nm	491nm;548nm
2	AQ; OR	GBAFP-TAF4-08188-AQOR	467nm;573nm	418nm;548nm
3	GO; GR	GBAFP-TAF4-08188-GOGR	551nm;515nm	525nm;491nm
4	GO; RE	GBAFP-TAF4-08188-GORE	551nm;599nm	525nm;580nm
5	GR; GO	GBAFP-TAF4-08188-GRGO	515nm;551nm	491nm;525nm
6	GR; RE	GBAFP-TAF4-08188-GRRE	515nm;599nm	491nm;580nm
7	OR; GR	GBAFP-TAF4-08188-ORGR	573nm;515nm	548nm;491nm
8	RE; GO	GBAFP-TAF4-08188-REGO	599nm;551nm	580nm;525nm
9	RE; GR	GBAFP-TAF4-08188-REGR	599nm;515nm	580nm;491nm

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