Gene-specific Break Apart Probe-TAF1

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Catalog:	GBAFP-TAF1-17964
Classification:	Gene-specific Break Apart Probes
Description:	Our Gene-specific Break Apart Probes usually target the flanks of the target gene (TAF1). Due to this design method, our probe products can detect chromosomal rearrangements, such as translocations, by FISH.The product usually consists of a reagent combination composed of a probe with a selected dye color and a hybridization reagent.
Application:	TAF1 Gene-specific Break Apart Probe is designed to detect potential TAF1 rearrangements. This probe has been confirmed on the metaphase and interphase chromosomes by FISH. We provide a variety of dye color combinations for Break Apart Probes for customers to choose from. Probe products not only provide some classic color combinations, but also provide customized probe services.
Quantity:	20 Tests
Probe Kits Volume (µL):	40 μL
Hybridization Solution (µL):	200 μL
Turnaround Time:	Within 10 Business Days
Shipping Time:	1-2 Day Expedited Shipping
Shipping Conditions:	-20℃
Storage Conditions:	Store at -20℃ and avoid light;

Gene Details

Gene Name	TATA-box Binding Protein Associated Factor 1
Gene Summary [Provided by RefSeq]	Initiation of transcription by RNA polymerase II requires the activities of more than 70 polypeptides. The protein that coordinates these activities is the basal transcription factor TFIID, which binds to the core promoter to position the polymerase properly, serves as the scaffold for assembly of the remainder of the transcription complex, and acts as a channel for regulatory signals. TFIID is composed of the TATA-binding protein (TBP) and a group of evolutionarily conserved proteins known as TBP-associated factors or TAFs. TAFs may participate in basal transcription, serve as coactivators, function in promoter recognition or modify general transcription factors (GTFs) to facilitate complex assembly and transcription initiation. This gene encodes the largest subunit of TFIID. This subunit binds to core promoter sequences encompassing the transcription start site. It also binds to activators and other transcriptional regulators, and these interactions affect the rate of transcription initiation. This subunit contains two independent protein kinase domains at the N- and C-terminals, but also possesses acetyltransferase activity and can act as a ubiquitin-activating/conjugating enzyme. Mutations in this gene result in Dystonia 3, torsion, X-linked, a dystonia-parkinsonism disorder. Alternative splicing of this gene results in multiple transcript variants. This gene is part of a complex transcription unit (TAF1/DYT3), wherein some transcript variants share exons with TAF1 as well as additional downstream DYT3 exons. [provided by RefSeq, Oct 2013]
Gene Symbol	TAF1
Location	Xq13.1
Chromosome	ChromosomeX
Coordinates	This gene maps to 70586113-70685855 in GRCh37 coordinates.
Species	Human

Order Sheet

Number	Dye Color	Order Name	Absorbance Maximum	Emission Maximum	Add to Cart
1	OR; GR	GBAFP-TAF1-17964-ORGR	573nm;515nm	548nm;491nm
2	AQ; OR	GBAFP-TAF1-17964-AQOR	467nm;573nm	418nm;548nm
3	GO; GR	GBAFP-TAF1-17964-GOGR	551nm;515nm	525nm;491nm
4	GO; RE	GBAFP-TAF1-17964-GORE	551nm;599nm	525nm;580nm
5	GR; GO	GBAFP-TAF1-17964-GRGO	515nm;551nm	491nm;525nm
6	GR; OR	GBAFP-TAF1-17964-GROR	515nm;573nm	491nm;548nm
7	GR; RE	GBAFP-TAF1-17964-GRRE	515nm;599nm	491nm;580nm
8	RE; GO	GBAFP-TAF1-17964-REGO	599nm;551nm	580nm;525nm
9	RE; GR	GBAFP-TAF1-17964-REGR	599nm;515nm	580nm;491nm

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