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| Catalog: | GBAFP-SLIT2-17176 |
| Classification: | Gene-specific Break Apart Probes |
| Description: | Our Gene-specific Break Apart Probes usually target the flanks of the target gene (SLIT2). Due to this design method, our probe products can detect chromosomal rearrangements, such as translocations, by FISH.The product usually consists of a reagent combination composed of a probe with a selected dye color and a hybridization reagent. |
| Application: | SLIT2 Gene-specific Break Apart Probe is designed to detect potential SLIT2 rearrangements. This probe has been confirmed on the metaphase and interphase chromosomes by FISH. We provide a variety of dye color combinations for Break Apart Probes for customers to choose from. Probe products not only provide some classic color combinations, but also provide customized probe services. |
| Quantity: | 20 Tests |
| Probe Kits Volume (µL): | 40 μL |
| Hybridization Solution (µL): | 200 μL |
| Turnaround Time: | Within 10 Business Days |
| Shipping Time: | 1-2 Day Expedited Shipping |
| Shipping Conditions: | -20℃ |
| Storage Conditions: | Store at -20℃ and avoid light; |
| Gene Name | Slit Guidance Ligand 2 |
| Gene Summary [Provided by RefSeq] | This gene encodes a member of the slit family of secreted glycoproteins, which are ligands for the Robo family of immunoglobulin receptors. Slit proteins play highly conserved roles in axon guidance and neuronal migration and may also have functions during other cell migration processes including leukocyte migration. Members of the slit family are characterized by an N-terminal signal peptide, four leucine-rich repeats, nine epidermal growth factor repeats, and a C-terminal cysteine knot. Proteolytic processing of this protein gives rise to an N-terminal fragment that contains the four leucine-rich repeats and five epidermal growth factor repeats and a C-terminal fragment that contains four epidermal growth factor repeats and the cysteine knot. Both full length and cleaved proteins are secreted extracellularly and can function in axon repulsion as well as other specific processes. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2015] |
| Gene Symbol | SLIT2 |
| Location | 4p15.31 |
| Chromosome | Chromosome4 |
| Coordinates | This gene maps to 20255234-20620788 in GRCh37 coordinates. |
| Species | Human |
| Number | Dye Color | Order Name | Absorbance Maximum | Emission Maximum | Add to Cart |
| 1 | OR; GR | GBAFP-SLIT2-17176-ORGR | 573nm;515nm | 548nm;491nm | |
| 2 | AQ; OR | GBAFP-SLIT2-17176-AQOR | 467nm;573nm | 418nm;548nm | |
| 3 | GO; GR | GBAFP-SLIT2-17176-GOGR | 551nm;515nm | 525nm;491nm | |
| 4 | GO; RE | GBAFP-SLIT2-17176-GORE | 551nm;599nm | 525nm;580nm | |
| 5 | GR; GO | GBAFP-SLIT2-17176-GRGO | 515nm;551nm | 491nm;525nm | |
| 6 | GR; OR | GBAFP-SLIT2-17176-GROR | 515nm;573nm | 491nm;548nm | |
| 7 | GR; RE | GBAFP-SLIT2-17176-GRRE | 515nm;599nm | 491nm;580nm | |
| 8 | RE; GO | GBAFP-SLIT2-17176-REGO | 599nm;551nm | 580nm;525nm | |
| 9 | RE; GR | GBAFP-SLIT2-17176-REGR | 599nm;515nm | 580nm;491nm |
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