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| Catalog: | GBAFP-SLC12A1-17025 |
| Classification: | Gene-specific Break Apart Probes |
| Description: | Our Gene-specific Break Apart Probes usually target the flanks of the target gene (SLC12A1). Due to this design method, our probe products can detect chromosomal rearrangements, such as translocations, by FISH.The product usually consists of a reagent combination composed of a probe with a selected dye color and a hybridization reagent. |
| Application: | SLC12A1 Gene-specific Break Apart Probe is designed to detect potential SLC12A1 rearrangements. This probe has been confirmed on the metaphase and interphase chromosomes by FISH. We provide a variety of dye color combinations for Break Apart Probes for customers to choose from. Probe products not only provide some classic color combinations, but also provide customized probe services. |
| Quantity: | 20 Tests |
| Probe Kits Volume (µL): | 40 μL |
| Hybridization Solution (µL): | 200 μL |
| Turnaround Time: | Within 10 Business Days |
| Shipping Time: | 1-2 Day Expedited Shipping |
| Shipping Conditions: | -20℃ |
| Storage Conditions: | Store at -20℃ and avoid light; |
| Gene Name | Solute Carrier Family 12 Member 1 |
| Gene Summary [Provided by RefSeq] | This gene encodes a kidney-specific sodium-potassium-chloride cotransporter that is expressed on the luminal membrane of renal epithelial cells of the thick ascending limb of Henle's loop and the macula densa. It plays a key role in concentrating urine and accounts for most of the NaCl resorption. It is sensitive to such diuretics as furosemide and bumetanide. Some Bartter-like syndromes result from defects in this gene. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Additional splice variants have been described but their biological validity in humans has not been experimentally proven.[provided by RefSeq, May 2010] |
| Gene Symbol | SLC12A1 |
| Location | 15q21.1 |
| Chromosome | Chromosome15 |
| Coordinates | This gene maps to 48498497-48596275 in GRCh37 coordinates. |
| Species | Human |
| Number | Dye Color | Order Name | Absorbance Maximum | Emission Maximum | Add to Cart |
| 1 | OR; GR | GBAFP-SLC12A1-17025-ORGR | 573nm;515nm | 548nm;491nm | |
| 2 | AQ; OR | GBAFP-SLC12A1-17025-AQOR | 467nm;573nm | 418nm;548nm | |
| 3 | GO; GR | GBAFP-SLC12A1-17025-GOGR | 551nm;515nm | 525nm;491nm | |
| 4 | GO; RE | GBAFP-SLC12A1-17025-GORE | 551nm;599nm | 525nm;580nm | |
| 5 | GR; GO | GBAFP-SLC12A1-17025-GRGO | 515nm;551nm | 491nm;525nm | |
| 6 | GR; OR | GBAFP-SLC12A1-17025-GROR | 515nm;573nm | 491nm;548nm | |
| 7 | GR; RE | GBAFP-SLC12A1-17025-GRRE | 515nm;599nm | 491nm;580nm | |
| 8 | RE; GO | GBAFP-SLC12A1-17025-REGO | 599nm;551nm | 580nm;525nm | |
| 9 | RE; GR | GBAFP-SLC12A1-17025-REGR | 599nm;515nm | 580nm;491nm |
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