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| Catalog: | GBAFP-RUNX2-16807 |
| Classification: | Gene-specific Break Apart Probes |
| Description: | Our Gene-specific Break Apart Probes usually target the flanks of the target gene (RUNX2). Due to this design method, our probe products can detect chromosomal rearrangements, such as translocations, by FISH.The product usually consists of a reagent combination composed of a probe with a selected dye color and a hybridization reagent. |
| Application: | RUNX2 Gene-specific Break Apart Probe is designed to detect potential RUNX2 rearrangements. This probe has been confirmed on the metaphase and interphase chromosomes by FISH. We provide a variety of dye color combinations for Break Apart Probes for customers to choose from. Probe products not only provide some classic color combinations, but also provide customized probe services. |
| Quantity: | 20 Tests |
| Probe Kits Volume (µL): | 40 μL |
| Hybridization Solution (µL): | 200 μL |
| Turnaround Time: | Within 10 Business Days |
| Shipping Time: | 1-2 Day Expedited Shipping |
| Shipping Conditions: | -20℃ |
| Storage Conditions: | Store at -20℃ and avoid light; |
| Gene Name | Runt Related Transcription Factor 2 |
| Gene Summary [Provided by RefSeq] | This gene is a member of the RUNX family of transcription factors and encodes a nuclear protein with an Runt DNA-binding domain. This protein is essential for osteoblastic differentiation and skeletal morphogenesis and acts as a scaffold for nucleic acids and regulatory factors involved in skeletal gene expression. The protein can bind DNA both as a monomer or, with more affinity, as a subunit of a heterodimeric complex. Two regions of potential trinucleotide repeat expansions are present in the N-terminal region of the encoded protein, and these and other mutations in this gene have been associated with the bone development disorder cleidocranial dysplasia (CCD). Transcript variants that encode different protein isoforms result from the use of alternate promoters as well as alternate splicing. [provided by RefSeq, Jul 2016] |
| Gene Symbol | RUNX2 |
| Location | 6p21.1 |
| Chromosome | Chromosome6 |
| Coordinates | This gene maps to 45296053-45518819 in GRCh37 coordinates. |
| Species | Human |
| Number | Dye Color | Order Name | Absorbance Maximum | Emission Maximum | Add to Cart |
| 1 | OR; GR | GBAFP-RUNX2-16807-ORGR | 573nm;515nm | 548nm;491nm | |
| 2 | AQ; OR | GBAFP-RUNX2-16807-AQOR | 467nm;573nm | 418nm;548nm | |
| 3 | GO; GR | GBAFP-RUNX2-16807-GOGR | 551nm;515nm | 525nm;491nm | |
| 4 | GO; RE | GBAFP-RUNX2-16807-GORE | 551nm;599nm | 525nm;580nm | |
| 5 | GR; GO | GBAFP-RUNX2-16807-GRGO | 515nm;551nm | 491nm;525nm | |
| 6 | GR; OR | GBAFP-RUNX2-16807-GROR | 515nm;573nm | 491nm;548nm | |
| 7 | GR; RE | GBAFP-RUNX2-16807-GRRE | 515nm;599nm | 491nm;580nm | |
| 8 | RE; GO | GBAFP-RUNX2-16807-REGO | 599nm;551nm | 580nm;525nm | |
| 9 | RE; GR | GBAFP-RUNX2-16807-REGR | 599nm;515nm | 580nm;491nm |
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