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Gene-specific Break Apart Probe-RUNX2

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Catalog: GBAFP-RUNX2-16807
Classification: Gene-specific Break Apart Probes
Description: Our Gene-specific Break Apart Probes usually target the flanks of the target gene (RUNX2). Due to this design method, our probe products can detect chromosomal rearrangements, such as translocations, by FISH.The product usually consists of a reagent combination composed of a probe with a selected dye color and a hybridization reagent.
Application: RUNX2 Gene-specific Break Apart Probe is designed to detect potential RUNX2 rearrangements. This probe has been confirmed on the metaphase and interphase chromosomes by FISH. We provide a variety of dye color combinations for Break Apart Probes for customers to choose from. Probe products not only provide some classic color combinations, but also provide customized probe services.
Quantity: 20 Tests
Probe Kits Volume (µL): 40 μL
Hybridization Solution (µL): 200 μL
Turnaround Time: Within 10 Business Days
Shipping Time: 1-2 Day Expedited Shipping
Shipping Conditions: -20℃
Storage Conditions: Store at -20℃ and avoid light;

Gene Details

Gene Name Runt Related Transcription Factor 2
Gene Summary [Provided by RefSeq] This gene is a member of the RUNX family of transcription factors and encodes a nuclear protein with an Runt DNA-binding domain. This protein is essential for osteoblastic differentiation and skeletal morphogenesis and acts as a scaffold for nucleic acids and regulatory factors involved in skeletal gene expression. The protein can bind DNA both as a monomer or, with more affinity, as a subunit of a heterodimeric complex. Two regions of potential trinucleotide repeat expansions are present in the N-terminal region of the encoded protein, and these and other mutations in this gene have been associated with the bone development disorder cleidocranial dysplasia (CCD). Transcript variants that encode different protein isoforms result from the use of alternate promoters as well as alternate splicing. [provided by RefSeq, Jul 2016]
Gene Symbol RUNX2
Location 6p21.1
Chromosome Chromosome6
Coordinates This gene maps to 45296053-45518819 in GRCh37 coordinates.
Species Human

Order Sheet

Number Dye Color Order Name Absorbance Maximum Emission Maximum Add to Cart
1 OR; GR GBAFP-RUNX2-16807-ORGR 573nm;515nm 548nm;491nm
2 AQ; OR GBAFP-RUNX2-16807-AQOR 467nm;573nm 418nm;548nm
3 GO; GR GBAFP-RUNX2-16807-GOGR 551nm;515nm 525nm;491nm
4 GO; RE GBAFP-RUNX2-16807-GORE 551nm;599nm 525nm;580nm
5 GR; GO GBAFP-RUNX2-16807-GRGO 515nm;551nm 491nm;525nm
6 GR; OR GBAFP-RUNX2-16807-GROR 515nm;573nm 491nm;548nm
7 GR; RE GBAFP-RUNX2-16807-GRRE 515nm;599nm 491nm;580nm
8 RE; GO GBAFP-RUNX2-16807-REGO 599nm;551nm 580nm;525nm
9 RE; GR GBAFP-RUNX2-16807-REGR 599nm;515nm 580nm;491nm

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