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| Catalog: | GBAFP-RPSA-16735 |
| Classification: | Gene-specific Break Apart Probes |
| Description: | Our Gene-specific Break Apart Probes usually target the flanks of the target gene (RPSA). Due to this design method, our probe products can detect chromosomal rearrangements, such as translocations, by FISH.The product usually consists of a reagent combination composed of a probe with a selected dye color and a hybridization reagent. |
| Application: | RPSA Gene-specific Break Apart Probe is designed to detect potential RPSA rearrangements. This probe has been confirmed on the metaphase and interphase chromosomes by FISH. We provide a variety of dye color combinations for Break Apart Probes for customers to choose from. Probe products not only provide some classic color combinations, but also provide customized probe services. |
| Quantity: | 20 Tests |
| Probe Kits Volume (µL): | 40 μL |
| Hybridization Solution (µL): | 200 μL |
| Turnaround Time: | Within 10 Business Days |
| Shipping Time: | 1-2 Day Expedited Shipping |
| Shipping Conditions: | -20℃ |
| Storage Conditions: | Store at -20℃ and avoid light; |
| Gene Name | Ribosomal Protein SA |
| Gene Summary [Provided by RefSeq] | Laminins, a family of extracellular matrix glycoproteins, are the major noncollagenous constituent of basement membranes. They have been implicated in a wide variety of biological processes including cell adhesion, differentiation, migration, signaling, neurite outgrowth and metastasis. Many of the effects of laminin are mediated through interactions with cell surface receptors. These receptors include members of the integrin family, as well as non-integrin laminin-binding proteins. This gene encodes a high-affinity, non-integrin family, laminin receptor 1. This receptor has been variously called 67 kD laminin receptor, 37 kD laminin receptor precursor (37LRP) and p40 ribosome-associated protein. The amino acid sequence of laminin receptor 1 is highly conserved through evolution, suggesting a key biological function. It has been observed that the level of the laminin receptor transcript is higher in colon carcinoma tissue and lung cancer cell line than their normal counterparts. Also, there is a correlation between the upregulation of this polypeptide in cancer cells and their invasive and metastatic phenotype. Multiple copies of this gene exist, however, most of them are pseudogenes thought to have arisen from retropositional events. Two alternatively spliced transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008] |
| Gene Symbol | RPSA |
| Location | 3p22.1 |
| Chromosome | Chromosome3 |
| Coordinates | This gene maps to 39448203-39454032 in GRCh37 coordinates. |
| Species | Human |
| Number | Dye Color | Order Name | Absorbance Maximum | Emission Maximum | Add to Cart |
| 1 | OR; GR | GBAFP-RPSA-16735-ORGR | 573nm;515nm | 548nm;491nm | |
| 2 | AQ; OR | GBAFP-RPSA-16735-AQOR | 467nm;573nm | 418nm;548nm | |
| 3 | GO; GR | GBAFP-RPSA-16735-GOGR | 551nm;515nm | 525nm;491nm | |
| 4 | GO; RE | GBAFP-RPSA-16735-GORE | 551nm;599nm | 525nm;580nm | |
| 5 | GR; GO | GBAFP-RPSA-16735-GRGO | 515nm;551nm | 491nm;525nm | |
| 6 | GR; OR | GBAFP-RPSA-16735-GROR | 515nm;573nm | 491nm;548nm | |
| 7 | GR; RE | GBAFP-RPSA-16735-GRRE | 515nm;599nm | 491nm;580nm | |
| 8 | RE; GO | GBAFP-RPSA-16735-REGO | 599nm;551nm | 580nm;525nm | |
| 9 | RE; GR | GBAFP-RPSA-16735-REGR | 599nm;515nm | 580nm;491nm |
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