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| Catalog: | GBAFP-PTPRC-16269 |
| Classification: | Gene-specific Break Apart Probes |
| Description: | Our Gene-specific Break Apart Probes usually target the flanks of the target gene (PTPRC). Due to this design method, our probe products can detect chromosomal rearrangements, such as translocations, by FISH.The product usually consists of a reagent combination composed of a probe with a selected dye color and a hybridization reagent. |
| Application: | PTPRC Gene-specific Break Apart Probe is designed to detect potential PTPRC rearrangements. This probe has been confirmed on the metaphase and interphase chromosomes by FISH. We provide a variety of dye color combinations for Break Apart Probes for customers to choose from. Probe products not only provide some classic color combinations, but also provide customized probe services. |
| Quantity: | 20 Tests |
| Probe Kits Volume (µL): | 40 μL |
| Hybridization Solution (µL): | 200 μL |
| Turnaround Time: | Within 10 Business Days |
| Shipping Time: | 1-2 Day Expedited Shipping |
| Shipping Conditions: | -20℃ |
| Storage Conditions: | Store at -20℃ and avoid light; |
| Gene Name | Protein Tyrosine Phosphatase, Receptor Type C |
| Gene Summary [Provided by RefSeq] | The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitosis, and oncogenic transformation. This PTP contains an extracellular domain, a single transmembrane segment and two tandem intracytoplasmic catalytic domains, and thus is classified as a receptor type PTP. This PTP has been shown to be an essential regulator of T- and B-cell antigen receptor signaling. It functions through either direct interaction with components of the antigen receptor complexes, or by activating various Src family kinases required for the antigen receptor signaling. This PTP also suppresses JAK kinases, and thus functions as a regulator of cytokine receptor signaling. Alternatively spliced transcripts variants of this gene, which encode distinct isoforms, have been reported. [provided by RefSeq, Jun 2012] |
| Gene Symbol | PTPRC |
| Location | 1q31.3-q32.1 |
| Chromosome | Chromosome1 |
| Coordinates | This gene maps to 198608136-198726545 in GRCh37 coordinates. |
| Species | Human |
| Number | Dye Color | Order Name | Absorbance Maximum | Emission Maximum | Add to Cart |
| 1 | OR; GR | GBAFP-PTPRC-16269-ORGR | 573nm;515nm | 548nm;491nm | |
| 2 | AQ; OR | GBAFP-PTPRC-16269-AQOR | 467nm;573nm | 418nm;548nm | |
| 3 | GO; GR | GBAFP-PTPRC-16269-GOGR | 551nm;515nm | 525nm;491nm | |
| 4 | GO; RE | GBAFP-PTPRC-16269-GORE | 551nm;599nm | 525nm;580nm | |
| 5 | GR; GO | GBAFP-PTPRC-16269-GRGO | 515nm;551nm | 491nm;525nm | |
| 6 | GR; OR | GBAFP-PTPRC-16269-GROR | 515nm;573nm | 491nm;548nm | |
| 7 | GR; RE | GBAFP-PTPRC-16269-GRRE | 515nm;599nm | 491nm;580nm | |
| 8 | RE; GO | GBAFP-PTPRC-16269-REGO | 599nm;551nm | 580nm;525nm | |
| 9 | RE; GR | GBAFP-PTPRC-16269-REGR | 599nm;515nm | 580nm;491nm |
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