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| Catalog: | GBAFP-PTPN22-06625 |
| Classification: | Gene-specific Break Apart Probes |
| Description: | Our Gene-specific Break Apart Probes usually target the flanks of the target gene (PTPN22). Due to this design method, our probe products can detect chromosomal rearrangements, such as translocations, by FISH.The product usually consists of a reagent combination composed of a probe with a selected dye color and a hybridization reagent. |
| Application: | PTPN22 Gene-specific Break Apart Probe is designed to detect potential PTPN22 rearrangements. This probe has been confirmed on the metaphase and interphase chromosomes by FISH. We provide a variety of dye color combinations for Break Apart Probes for customers to choose from. Probe products not only provide some classic color combinations, but also provide customized probe services. |
| Quantity: | 20 Tests |
| Probe Kits Volume (µL): | 40 μL |
| Hybridization Solution (µL): | 200 μL |
| Turnaround Time: | Within 10 Business Days |
| Shipping Time: | 1-2 Day Expedited Shipping |
| Shipping Conditions: | -20℃ |
| Storage Conditions: | Store at -20℃ and avoid light; |
| Gene Name | Protein Tyrosine Phosphatase, Non-receptor Type 22 |
| Gene Summary [Provided by RefSeq] | This gene encodes of member of the non-receptor class 4 subfamily of the protein-tyrosine phosphatase family. The encoded protein is a lymphoid-specific intracellular phosphatase that associates with the molecular adapter protein CBL and may be involved in regulating CBL function in the T-cell receptor signaling pathway. Mutations in this gene may be associated with a range of autoimmune disorders including Type 1 Diabetes, rheumatoid arthritis, systemic lupus erythematosus and Graves' disease. Alternatively spliced transcript variants encoding distinct isoforms have been described. [provided by RefSeq, Mar 2009] |
| Gene Symbol | PTPN22 |
| Location | 1p13.2 |
| Chromosome | Chromosome1 |
| Coordinates | This gene maps to 114356432-114414375 in GRCh37 coordinates. |
| Species | Human |
| Number | Dye Color | Order Name | Absorbance Maximum | Emission Maximum | Add to Cart |
| 1 | GR; OR | GBAFP-PTPN22-06625-GROR | 515nm;573nm | 491nm;548nm | |
| 2 | AQ; OR | GBAFP-PTPN22-06625-AQOR | 467nm;573nm | 418nm;548nm | |
| 3 | GO; GR | GBAFP-PTPN22-06625-GOGR | 551nm;515nm | 525nm;491nm | |
| 4 | GO; RE | GBAFP-PTPN22-06625-GORE | 551nm;599nm | 525nm;580nm | |
| 5 | GR; GO | GBAFP-PTPN22-06625-GRGO | 515nm;551nm | 491nm;525nm | |
| 6 | GR; RE | GBAFP-PTPN22-06625-GRRE | 515nm;599nm | 491nm;580nm | |
| 7 | OR; GR | GBAFP-PTPN22-06625-ORGR | 573nm;515nm | 548nm;491nm | |
| 8 | RE; GO | GBAFP-PTPN22-06625-REGO | 599nm;551nm | 580nm;525nm | |
| 9 | RE; GR | GBAFP-PTPN22-06625-REGR | 599nm;515nm | 580nm;491nm |
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