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Gene-specific Break Apart Probe-PTAFR

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Catalog: GBAFP-PTAFR-06641
Classification: Gene-specific Break Apart Probes
Description: Our Gene-specific Break Apart Probes usually target the flanks of the target gene (PTAFR). Due to this design method, our probe products can detect chromosomal rearrangements, such as translocations, by FISH.The product usually consists of a reagent combination composed of a probe with a selected dye color and a hybridization reagent.
Application: PTAFR Gene-specific Break Apart Probe is designed to detect potential PTAFR rearrangements. This probe has been confirmed on the metaphase and interphase chromosomes by FISH. We provide a variety of dye color combinations for Break Apart Probes for customers to choose from. Probe products not only provide some classic color combinations, but also provide customized probe services.
Quantity: 20 Tests
Probe Kits Volume (µL): 40 μL
Hybridization Solution (µL): 200 μL
Turnaround Time: Within 10 Business Days
Shipping Time: 1-2 Day Expedited Shipping
Shipping Conditions: -20℃
Storage Conditions: Store at -20℃ and avoid light;

Gene Details

Gene Name Platelet Activating Factor Receptor
Gene Summary [Provided by RefSeq] This gene encodes a seven-transmembrane G-protein-coupled receptor for platelet-activating factor (PAF) that localizes to lipid rafts and/or caveolae in the cell membrane. PAF (1-0-alkyl-2-acetyl-sn-glycero-3-phosphorylcholine) is a phospholipid that plays a significant role in oncogenic transformation, tumor growth, angiogenesis, metastasis, and pro-inflammatory processes. Binding of PAF to the PAF-receptor (PAFR) stimulates numerous signal transduction pathways including phospholipase C, D, A2, mitogen-activated protein kinases (MAPKs), and the phosphatidylinositol-calcium second messenger system. Following PAFR activation, cells become rapidly desensitized and this refractory state is dependent on PAFR phosphorylation, internalization, and down-regulation. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2011]
Gene Symbol PTAFR
Location 1p35.3
Chromosome Chromosome1
Coordinates This gene maps to 28473676-28520447 in GRCh37 coordinates.
Species Human

Order Sheet

Number Dye Color Order Name Absorbance Maximum Emission Maximum Add to Cart
1 GR; OR GBAFP-PTAFR-06641-GROR 515nm;573nm 491nm;548nm
2 AQ; OR GBAFP-PTAFR-06641-AQOR 467nm;573nm 418nm;548nm
3 GO; GR GBAFP-PTAFR-06641-GOGR 551nm;515nm 525nm;491nm
4 GO; RE GBAFP-PTAFR-06641-GORE 551nm;599nm 525nm;580nm
5 GR; GO GBAFP-PTAFR-06641-GRGO 515nm;551nm 491nm;525nm
6 GR; RE GBAFP-PTAFR-06641-GRRE 515nm;599nm 491nm;580nm
7 OR; GR GBAFP-PTAFR-06641-ORGR 573nm;515nm 548nm;491nm
8 RE; GO GBAFP-PTAFR-06641-REGO 599nm;551nm 580nm;525nm
9 RE; GR GBAFP-PTAFR-06641-REGR 599nm;515nm 580nm;491nm

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