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| Catalog: | GBAFP-PTAFR-06641 |
| Classification: | Gene-specific Break Apart Probes |
| Description: | Our Gene-specific Break Apart Probes usually target the flanks of the target gene (PTAFR). Due to this design method, our probe products can detect chromosomal rearrangements, such as translocations, by FISH.The product usually consists of a reagent combination composed of a probe with a selected dye color and a hybridization reagent. |
| Application: | PTAFR Gene-specific Break Apart Probe is designed to detect potential PTAFR rearrangements. This probe has been confirmed on the metaphase and interphase chromosomes by FISH. We provide a variety of dye color combinations for Break Apart Probes for customers to choose from. Probe products not only provide some classic color combinations, but also provide customized probe services. |
| Quantity: | 20 Tests |
| Probe Kits Volume (µL): | 40 μL |
| Hybridization Solution (µL): | 200 μL |
| Turnaround Time: | Within 10 Business Days |
| Shipping Time: | 1-2 Day Expedited Shipping |
| Shipping Conditions: | -20℃ |
| Storage Conditions: | Store at -20℃ and avoid light; |
| Gene Name | Platelet Activating Factor Receptor |
| Gene Summary [Provided by RefSeq] | This gene encodes a seven-transmembrane G-protein-coupled receptor for platelet-activating factor (PAF) that localizes to lipid rafts and/or caveolae in the cell membrane. PAF (1-0-alkyl-2-acetyl-sn-glycero-3-phosphorylcholine) is a phospholipid that plays a significant role in oncogenic transformation, tumor growth, angiogenesis, metastasis, and pro-inflammatory processes. Binding of PAF to the PAF-receptor (PAFR) stimulates numerous signal transduction pathways including phospholipase C, D, A2, mitogen-activated protein kinases (MAPKs), and the phosphatidylinositol-calcium second messenger system. Following PAFR activation, cells become rapidly desensitized and this refractory state is dependent on PAFR phosphorylation, internalization, and down-regulation. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2011] |
| Gene Symbol | PTAFR |
| Location | 1p35.3 |
| Chromosome | Chromosome1 |
| Coordinates | This gene maps to 28473676-28520447 in GRCh37 coordinates. |
| Species | Human |
| Number | Dye Color | Order Name | Absorbance Maximum | Emission Maximum | Add to Cart |
| 1 | GR; OR | GBAFP-PTAFR-06641-GROR | 515nm;573nm | 491nm;548nm | |
| 2 | AQ; OR | GBAFP-PTAFR-06641-AQOR | 467nm;573nm | 418nm;548nm | |
| 3 | GO; GR | GBAFP-PTAFR-06641-GOGR | 551nm;515nm | 525nm;491nm | |
| 4 | GO; RE | GBAFP-PTAFR-06641-GORE | 551nm;599nm | 525nm;580nm | |
| 5 | GR; GO | GBAFP-PTAFR-06641-GRGO | 515nm;551nm | 491nm;525nm | |
| 6 | GR; RE | GBAFP-PTAFR-06641-GRRE | 515nm;599nm | 491nm;580nm | |
| 7 | OR; GR | GBAFP-PTAFR-06641-ORGR | 573nm;515nm | 548nm;491nm | |
| 8 | RE; GO | GBAFP-PTAFR-06641-REGO | 599nm;551nm | 580nm;525nm | |
| 9 | RE; GR | GBAFP-PTAFR-06641-REGR | 599nm;515nm | 580nm;491nm |
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