Gene-specific Break Apart Probe-PSMC2

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Catalog:	GBAFP-PSMC2-16163
Classification:	Gene-specific Break Apart Probes
Description:	Our Gene-specific Break Apart Probes usually target the flanks of the target gene (PSMC2). Due to this design method, our probe products can detect chromosomal rearrangements, such as translocations, by FISH.The product usually consists of a reagent combination composed of a probe with a selected dye color and a hybridization reagent.
Application:	PSMC2 Gene-specific Break Apart Probe is designed to detect potential PSMC2 rearrangements. This probe has been confirmed on the metaphase and interphase chromosomes by FISH. We provide a variety of dye color combinations for Break Apart Probes for customers to choose from. Probe products not only provide some classic color combinations, but also provide customized probe services.
Quantity:	20 Tests
Probe Kits Volume (µL):	40 μL
Hybridization Solution (µL):	200 μL
Turnaround Time:	Within 10 Business Days
Shipping Time:	1-2 Day Expedited Shipping
Shipping Conditions:	-20℃
Storage Conditions:	Store at -20℃ and avoid light;

Gene Details

Gene Name	Proteasome 26S Subunit, ATPase 2
Gene Summary [Provided by RefSeq]	The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes one of the ATPase subunits, a member of the triple-A family of ATPases which have a chaperone-like activity. This subunit has been shown to interact with several of the basal transcription factors so, in addition to participation in proteasome functions, this subunit may participate in the regulation of transcription. This subunit may also compete with PSMC3 for binding to the HIV tat protein to regulate the interaction between the viral protein and the transcription complex. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Mar 2011]
Gene Symbol	PSMC2
Location	7q22.1
Chromosome	Chromosome7
Coordinates	This gene maps to 102987970-103009842 in GRCh37 coordinates.
Species	Human

Order Sheet

Number	Dye Color	Order Name	Absorbance Maximum	Emission Maximum	Add to Cart
1	OR; GR	GBAFP-PSMC2-16163-ORGR	573nm;515nm	548nm;491nm
2	AQ; OR	GBAFP-PSMC2-16163-AQOR	467nm;573nm	418nm;548nm
3	GO; GR	GBAFP-PSMC2-16163-GOGR	551nm;515nm	525nm;491nm
4	GO; RE	GBAFP-PSMC2-16163-GORE	551nm;599nm	525nm;580nm
5	GR; GO	GBAFP-PSMC2-16163-GRGO	515nm;551nm	491nm;525nm
6	GR; OR	GBAFP-PSMC2-16163-GROR	515nm;573nm	491nm;548nm
7	GR; RE	GBAFP-PSMC2-16163-GRRE	515nm;599nm	491nm;580nm
8	RE; GO	GBAFP-PSMC2-16163-REGO	599nm;551nm	580nm;525nm
9	RE; GR	GBAFP-PSMC2-16163-REGR	599nm;515nm	580nm;491nm

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