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Gene-specific Break Apart Probe-PRNP

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Catalog: GBAFP-PRNP-16098
Classification: Gene-specific Break Apart Probes
Description: Our Gene-specific Break Apart Probes usually target the flanks of the target gene (PRNP). Due to this design method, our probe products can detect chromosomal rearrangements, such as translocations, by FISH.The product usually consists of a reagent combination composed of a probe with a selected dye color and a hybridization reagent.
Application: PRNP Gene-specific Break Apart Probe is designed to detect potential PRNP rearrangements. This probe has been confirmed on the metaphase and interphase chromosomes by FISH. We provide a variety of dye color combinations for Break Apart Probes for customers to choose from. Probe products not only provide some classic color combinations, but also provide customized probe services.
Quantity: 20 Tests
Probe Kits Volume (µL): 40 μL
Hybridization Solution (µL): 200 μL
Turnaround Time: Within 10 Business Days
Shipping Time: 1-2 Day Expedited Shipping
Shipping Conditions: -20℃
Storage Conditions: Store at -20℃ and avoid light;

Gene Details

Gene Name Prion Protein
Gene Summary [Provided by RefSeq] The protein encoded by this gene is a membrane glycosylphosphatidylinositol-anchored glycoprotein that tends to aggregate into rod-like structures. The encoded protein contains a highly unstable region of five tandem octapeptide repeats. This gene is found on chromosome 20, approximately 20 kbp upstream of a gene which encodes a biochemically and structurally similar protein to the one encoded by this gene. Mutations in the repeat region as well as elsewhere in this gene have been associated with Creutzfeldt-Jakob disease, fatal familial insomnia, Gerstmann-Straussler disease, Huntington disease-like 1, and kuru. An overlapping open reading frame has been found for this gene that encodes a smaller, structurally unrelated protein, AltPrp. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2014]
Gene Symbol PRNP
Location 20p13
Chromosome Chromosome20
Coordinates This gene maps to 4666796-4682234 in GRCh37 coordinates.
Species Human

Order Sheet

Number Dye Color Order Name Absorbance Maximum Emission Maximum Add to Cart
1 OR; GR GBAFP-PRNP-16098-ORGR 573nm;515nm 548nm;491nm
2 AQ; OR GBAFP-PRNP-16098-AQOR 467nm;573nm 418nm;548nm
3 GO; GR GBAFP-PRNP-16098-GOGR 551nm;515nm 525nm;491nm
4 GO; RE GBAFP-PRNP-16098-GORE 551nm;599nm 525nm;580nm
5 GR; GO GBAFP-PRNP-16098-GRGO 515nm;551nm 491nm;525nm
6 GR; OR GBAFP-PRNP-16098-GROR 515nm;573nm 491nm;548nm
7 GR; RE GBAFP-PRNP-16098-GRRE 515nm;599nm 491nm;580nm
8 RE; GO GBAFP-PRNP-16098-REGO 599nm;551nm 580nm;525nm
9 RE; GR GBAFP-PRNP-16098-REGR 599nm;515nm 580nm;491nm

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