Gene-specific Break Apart Probe-PRKAR1A

Add to Cart

Catalog:	GBAFP-PRKAR1A-16104
Classification:	Gene-specific Break Apart Probes
Description:	Our Gene-specific Break Apart Probes usually target the flanks of the target gene (PRKAR1A). Due to this design method, our probe products can detect chromosomal rearrangements, such as translocations, by FISH.The product usually consists of a reagent combination composed of a probe with a selected dye color and a hybridization reagent.
Application:	PRKAR1A Gene-specific Break Apart Probe is designed to detect potential PRKAR1A rearrangements. This probe has been confirmed on the metaphase and interphase chromosomes by FISH. We provide a variety of dye color combinations for Break Apart Probes for customers to choose from. Probe products not only provide some classic color combinations, but also provide customized probe services.
Quantity:	20 Tests
Probe Kits Volume (µL):	40 μL
Hybridization Solution (µL):	200 μL
Turnaround Time:	Within 10 Business Days
Shipping Time:	1-2 Day Expedited Shipping
Shipping Conditions:	-20℃
Storage Conditions:	Store at -20℃ and avoid light;

Gene Details

Gene Name	Protein Kinase CAMP-dependent Type I Regulatory Subunit Alpha
Gene Summary [Provided by RefSeq]	cAMP is a signaling molecule important for a variety of cellular functions. cAMP exerts its effects by activating the cAMP-dependent protein kinase, which transduces the signal through phosphorylation of different target proteins. The inactive kinase holoenzyme is a tetramer composed of two regulatory and two catalytic subunits. cAMP causes the dissociation of the inactive holoenzyme into a dimer of regulatory subunits bound to four cAMP and two free monomeric catalytic subunits. Four different regulatory subunits and three catalytic subunits have been identified in humans. This gene encodes one of the regulatory subunits. This protein was found to be a tissue-specific extinguisher that down-regulates the expression of seven liver genes in hepatoma x fibroblast hybrids. Mutations in this gene cause Carney complex (CNC). This gene can fuse to the RET protooncogene by gene rearrangement and form the thyroid tumor-specific chimeric oncogene known as PTC2. A nonconventional nuclear localization sequence (NLS) has been found for this protein which suggests a role in DNA replication via the protein serving as a nuclear transport protein for the second subunit of the Replication Factor C (RFC40). Several alternatively spliced transcript variants encoding two different isoforms have been observed. [provided by RefSeq, Jan 2013]
Gene Symbol	PRKAR1A
Location	17q24.2
Chromosome	Chromosome17
Coordinates	This gene maps to 66508109-66528910 in GRCh37 coordinates.
Species	Human

Order Sheet

Number	Dye Color	Order Name	Absorbance Maximum	Emission Maximum	Add to Cart
1	OR; GR	GBAFP-PRKAR1A-16104-ORGR	573nm;515nm	548nm;491nm
2	AQ; OR	GBAFP-PRKAR1A-16104-AQOR	467nm;573nm	418nm;548nm
3	GO; GR	GBAFP-PRKAR1A-16104-GOGR	551nm;515nm	525nm;491nm
4	GO; RE	GBAFP-PRKAR1A-16104-GORE	551nm;599nm	525nm;580nm
5	GR; GO	GBAFP-PRKAR1A-16104-GRGO	515nm;551nm	491nm;525nm
6	GR; OR	GBAFP-PRKAR1A-16104-GROR	515nm;573nm	491nm;548nm
7	GR; RE	GBAFP-PRKAR1A-16104-GRRE	515nm;599nm	491nm;580nm
8	RE; GO	GBAFP-PRKAR1A-16104-REGO	599nm;551nm	580nm;525nm
9	RE; GR	GBAFP-PRKAR1A-16104-REGR	599nm;515nm	580nm;491nm

Other Products

Products

CONTACT SUPPORT

Online Inquiry