Gene-specific Break Apart Probe-PCBP2

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Catalog:	GBAFP-PCBP2-15563
Classification:	Gene-specific Break Apart Probes
Description:	Our Gene-specific Break Apart Probes usually target the flanks of the target gene (PCBP2). Due to this design method, our probe products can detect chromosomal rearrangements, such as translocations, by FISH.The product usually consists of a reagent combination composed of a probe with a selected dye color and a hybridization reagent.
Application:	PCBP2 Gene-specific Break Apart Probe is designed to detect potential PCBP2 rearrangements. This probe has been confirmed on the metaphase and interphase chromosomes by FISH. We provide a variety of dye color combinations for Break Apart Probes for customers to choose from. Probe products not only provide some classic color combinations, but also provide customized probe services.
Quantity:	20 Tests
Probe Kits Volume (µL):	40 μL
Hybridization Solution (µL):	200 μL
Turnaround Time:	Within 10 Business Days
Shipping Time:	1-2 Day Expedited Shipping
Shipping Conditions:	-20℃
Storage Conditions:	Store at -20℃ and avoid light;

Gene Details

Gene Name	Poly(rC) Binding Protein 2
Gene Summary [Provided by RefSeq]	The protein encoded by this gene appears to be multifunctional. Along with PCBP-1 and hnRNPK, it is one of the major cellular poly(rC)-binding proteins. The encoded protein contains three K-homologous (KH) domains which may be involved in RNA binding. Together with PCBP-1, this protein also functions as a translational coactivator of poliovirus RNA via a sequence-specific interaction with stem-loop IV of the IRES, promoting poliovirus RNA replication by binding to its 5'-terminal cloverleaf structure. It has also been implicated in translational control of the 15-lipoxygenase mRNA, human papillomavirus type 16 L2 mRNA, and hepatitis A virus RNA. The encoded protein is also suggested to play a part in formation of a sequence-specific alpha-globin mRNP complex which is associated with alpha-globin mRNA stability. This multiexon structural mRNA is thought to be retrotransposed to generate PCBP-1, an intronless gene with functions similar to that of PCBP2. This gene and PCBP-1 have paralogous genes (PCBP3 and PCBP4) which are thought to have arisen as a result of duplication events of entire genes. This gene also has two processed pseudogenes (PCBP2P1 and PCBP2P2). Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2018]
Gene Symbol	PCBP2
Location	12q13.13
Chromosome	Chromosome12
Coordinates	This gene maps to 53845885-53874946 in GRCh37 coordinates.
Species	Human

Order Sheet

Number	Dye Color	Order Name	Absorbance Maximum	Emission Maximum	Add to Cart
1	OR; GR	GBAFP-PCBP2-15563-ORGR	573nm;515nm	548nm;491nm
2	AQ; OR	GBAFP-PCBP2-15563-AQOR	467nm;573nm	418nm;548nm
3	GO; GR	GBAFP-PCBP2-15563-GOGR	551nm;515nm	525nm;491nm
4	GO; RE	GBAFP-PCBP2-15563-GORE	551nm;599nm	525nm;580nm
5	GR; GO	GBAFP-PCBP2-15563-GRGO	515nm;551nm	491nm;525nm
6	GR; OR	GBAFP-PCBP2-15563-GROR	515nm;573nm	491nm;548nm
7	GR; RE	GBAFP-PCBP2-15563-GRRE	515nm;599nm	491nm;580nm
8	RE; GO	GBAFP-PCBP2-15563-REGO	599nm;551nm	580nm;525nm
9	RE; GR	GBAFP-PCBP2-15563-REGR	599nm;515nm	580nm;491nm

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