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| Catalog: | GBAFP-OPTN-15238 |
| Classification: | Gene-specific Break Apart Probes |
| Description: | Our Gene-specific Break Apart Probes usually target the flanks of the target gene (OPTN). Due to this design method, our probe products can detect chromosomal rearrangements, such as translocations, by FISH.The product usually consists of a reagent combination composed of a probe with a selected dye color and a hybridization reagent. |
| Application: | OPTN Gene-specific Break Apart Probe is designed to detect potential OPTN rearrangements. This probe has been confirmed on the metaphase and interphase chromosomes by FISH. We provide a variety of dye color combinations for Break Apart Probes for customers to choose from. Probe products not only provide some classic color combinations, but also provide customized probe services. |
| Quantity: | 20 Tests |
| Probe Kits Volume (µL): | 40 μL |
| Hybridization Solution (µL): | 200 μL |
| Turnaround Time: | Within 10 Business Days |
| Shipping Time: | 1-2 Day Expedited Shipping |
| Shipping Conditions: | -20℃ |
| Storage Conditions: | Store at -20℃ and avoid light; |
| Gene Name | Optineurin |
| Gene Summary [Provided by RefSeq] | This gene encodes the coiled-coil containing protein optineurin. Optineurin may play a role in normal-tension glaucoma and adult-onset primary open angle glaucoma. Optineurin interacts with adenovirus E3-14.7K protein and may utilize tumor necrosis factor-alpha or Fas-ligand pathways to mediate apoptosis, inflammation or vasoconstriction. Optineurin may also function in cellular morphogenesis and membrane trafficking, vesicle trafficking, and transcription activation through its interactions with the RAB8, huntingtin, and transcription factor IIIA proteins. Alternative splicing results in multiple transcript variants encoding the same protein. [provided by RefSeq, Jul 2008] |
| Gene Symbol | OPTN |
| Location | 10p13 |
| Chromosome | Chromosome10 |
| Coordinates | This gene maps to 13142081-13180276 in GRCh37 coordinates. |
| Species | Human |
| Number | Dye Color | Order Name | Absorbance Maximum | Emission Maximum | Add to Cart |
| 1 | OR; GR | GBAFP-OPTN-15238-ORGR | 573nm;515nm | 548nm;491nm | |
| 2 | AQ; OR | GBAFP-OPTN-15238-AQOR | 467nm;573nm | 418nm;548nm | |
| 3 | GO; GR | GBAFP-OPTN-15238-GOGR | 551nm;515nm | 525nm;491nm | |
| 4 | GO; RE | GBAFP-OPTN-15238-GORE | 551nm;599nm | 525nm;580nm | |
| 5 | GR; GO | GBAFP-OPTN-15238-GRGO | 515nm;551nm | 491nm;525nm | |
| 6 | GR; OR | GBAFP-OPTN-15238-GROR | 515nm;573nm | 491nm;548nm | |
| 7 | GR; RE | GBAFP-OPTN-15238-GRRE | 515nm;599nm | 491nm;580nm | |
| 8 | RE; GO | GBAFP-OPTN-15238-REGO | 599nm;551nm | 580nm;525nm | |
| 9 | RE; GR | GBAFP-OPTN-15238-REGR | 599nm;515nm | 580nm;491nm |
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